• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PCGF3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6143428

MBS6143428 is an antibody targeting PCGF3. Also known as PCGF3 (RING Finger Protein 3, RNF3, RING Finger Protein 3A, RNF3A, DONG1, Polycomb Group RING Finger Protein 3) (Biotin). Reactive in Human. Host: Mouse. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PCGF3, Monoclonal Antibody
Full Product Name
PCGF3 (RING Finger Protein 3, RNF3, RING Finger Protein 3A, RNF3A, DONG1, Polycomb Group RING Finger Protein 3) (Biotin)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1F1
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human PCGF3.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
3D Structure
ModBase 3D Structure for Q3KNV8
Immunogen
Partial recombinant corresponding to aa133-242 from PCGF3 (NP_006306) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
SNKEAAEEKPEEDNDYHRSDEQVSICLECNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPKMDLL
Conjugate
Biotin
Applications Tested/Suitable for anti-PCGF3 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-PCGF3 antibody
IHC-P: 3ug/ml
Applications are based on unconjugated antibody.

Testing Data of anti-PCGF3 antibody

Immunoperoxidase of monoclonal antibody to PCGF3 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3ug/ml]
Mouse Anti-PCGF3 Monoclonal Antibody – Cat# MBS6143428

Testing Data of anti-PCGF3 antibody

Detection limit for recombinant GST tagged PCGF3 is ~3ng/ml as a capture antibody.
Mouse Anti-PCGF3 Monoclonal Antibody, Testing Data – Cat# MBS6143428

Other Notes

Small volumes of anti-PCGF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PCGF3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens polycomb group ring finger 3 (PCGF3), transcript variant 2, mRNA
NCBI Official Synonym Full Names
polycomb group ring finger 3
NCBI Official Symbol
PCGF3
NCBI Official Synonym Symbols
RNF3; DONG1; RNF3A
UniProt Protein Name
Polycomb group RING finger protein 3
UniProt Synonym Protein Names
RING finger protein 3A
UniProt Gene Name
PCGF3
UniProt Synonym Gene Names
RNF3; RNF3A
NCBI Protein Information
polycomb group RING finger protein 3

NCBI Summary for PCGF3

The protein encoded by this gene contains a C3HC4 type RING finger, which is a motif known to be involved in protein-protein interactions. The specific function of this protein has not yet been determined. [provided by RefSeq, Jul 2008]

UniProt Comments for PCGF3

PCGF3: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: nucleoplasm; nucleus; PcG protein complex; X chromosome

Molecular Function: metal ion binding; protein binding

Biological Process: regulation of transcription, DNA-templated; transcription, DNA-dependent
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000