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Parathyroid Hormone Receptor Type 2 (PTH2R) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS614362

MBS614362 is an antibody targeting PTH2R. Also known as Parathyroid Hormone Receptor Type 2 (PTH Receptor 2, PTHR2, Parathyroid Hormone 2 Receptor, PTH2 Receptor, PTH-2 Receptor, PTH2R, Parathyroid Hormone Receptor Precursor). Reactive in Rat. Host: Rabbit. More details

$940 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Parathyroid Hormone Receptor Type 2 (PTH2R), Polyclonal Antibody
Full Product Name
Parathyroid Hormone Receptor Type 2 (PTH Receptor 2, PTHR2, Parathyroid Hormone 2 Receptor, PTH2 Receptor, PTH-2 Receptor, PTH2R, Parathyroid Hormone Receptor Precursor)
Product Gene Name
Product Synonym Names
Anti -Parathyroid Hormone Receptor Type 2 (PTH Receptor 2, PTHR2, Parathyroid Hormone 2 Receptor, PTH2 Receptor, PTH-2 Receptor, PTH2R, Parathyroid Hormone Receptor Precursor)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Supplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material.
Purity/Purification
Serum
Serum
Specificity
Specificity has been shown by Western blot. A band of 63kD corresponding to the theoretical molecular weight of Parathyroid hormone receptor is easily detectable by WB. Absorption of the antiserum with the immunising peptide abolished the binding of the antibody to the target hence detectability of the band. Species Crossreactivity: Rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
62,236 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (209224569..209359231). Location: 2q33
OMIM
601469
3D Structure
ModBase 3D Structure for P49190
Immunogen
A synthetic peptide (RQIDSHVTLP GYVWSSSEQD C) of rat Parathyroid hormone receptor protein (aa: 481-501) conjugated to KLH.
Cellular Localization
Membrane; multi-pass membrane protein.

Product Categories/Family for anti-PTH2R antibody

Applications Tested/Suitable for anti-PTH2R antibody
Western Blot (WB)
Application Notes for anti-PTH2R antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-PTH2R antibody

Western blot analysis of rat brain using MBS614362 isolated a major band of 63 kDa corresponding to the theoretical molecular weight of Parathyroid hormone receptor.
Rabbit Anti-PTH2R Polyclonal Antibody – Cat# MBS614362

Other Notes

Small volumes of anti-PTH2R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTH2R. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
parathyroid hormone 2 receptor
NCBI Official Synonym Full Names
parathyroid hormone 2 receptor
NCBI Official Symbol
PTH2R
NCBI Official Synonym Symbols
PTHR2
UniProt Protein Name
Parathyroid hormone 2 receptor
UniProt Gene Name
PTH2R
UniProt Synonym Gene Names
PTHR2; PTH2 receptor
UniProt Entry Name
PTH2R_HUMAN
NCBI Protein Information
parathyroid hormone 2 receptor; PTH2 receptor; parathyroid hormone receptor 2

NCBI Summary for PTH2R

The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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UniProt Comments for PTH2R

PTH2R: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 2; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: parathyroid hormone receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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