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CoREST Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS614430

Brain type II sodium channels are important in neuronal phenotyping and are only seen at high levels in neurons. Studies have shown that CoREST functions as a corepressor for REST. This interaction between REST and CoREST is accomplished by means of a single… More details

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Product Overview

Online Datasheet in PDF
Product Name
CoREST, Polyclonal Antibody
Full Product Name
Anti - CoREST (REST corepressor 1, Protein CoREST, KIAA0071, RCOR, RCOR1)
Product Gene Name
Product Synonym Names
CoREST (REST corepressor 1, Protein CoREST, KIAA0071, RCOR, RCOR1)
Clonality
Polyclonal
Isotype
IgG
Host
Host: Rabbit
Source: Human
Species Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified
Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide before the addition of glycerol to 30%.
Purity/Purification
Purified by Protein A affinity chromatography.
Concentration
~1mg/ml (lot specific)
Specificity
Recognizes human CoREST, Mr ~66kD. Species Crossreactivity: Mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
53,028 Da
Chromosome Location
Chromosome: 14; NC_000014.8 (103059233..103196913). Location: 14q32.31
OMIM
607675
3D Structure
ModBase 3D Structure for Q9UKL0
Immunogen
GST fusion protein corresponding to residues 109-293 of human CoREST.

Product Categories/Family for anti-CoREST antibody

Applications Tested/Suitable for anti-CoREST antibody
Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry
Application Notes for anti-CoREST antibody
Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested.
Dilution: Immunoblot Analysis: 0.1-0.5ug/ml detects CoREST in RIPA lysates from A431, 3T3/A31, Jurkat, and Hela cells. Reported to be detected in RIPA lysates from HEK 293, L6, PC12, C6 cells and liver, muscle, heart and brain tissue.
Immunoprecipitation: 2.5ug immunoprecipitates CoREST from 250ug of A431 RIPA lysate.
Immunocytochemistry: Positive immunostaining for CoREST in cells fixed with 4% paraformaldehyde pH 7.3 for 10-15 minutes
Immunohistochemistry: Reported to detect CoREST in tissue sections.

Western Blot (WB) of anti-CoREST antibody

Western Blot of A431 cell lysate using MBS614430 (0.1ug/ml).
Rabbit Anti-CoREST Polyclonal Antibody – Cat# MBS614430

Product References and Citations for anti-CoREST antibody

• 1. Lunyak, V. V., et. al., Science 298: 1747-1752, 2003.
• 2. Ballas, N., et. al., Neuron 31: 353-365, 2001.
• 3. Andres, M. E., et. al., PNAS 96: 9873-9878, 1999.

Other Notes

Small volumes of anti-CoREST antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CoREST purchase

MBS614430 is an antibody targeting CoREST. Also known as Anti - CoREST (REST corepressor 1, Protein CoREST, KIAA0071, RCOR, RCOR1). Reactive in Human, Mouse, Rat. Host: Rabbit
Source: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CoREST. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
CoREST protein
NCBI Official Synonym Full Names
REST corepressor 1
NCBI Official Symbol
RCOR1
NCBI Official Synonym Symbols
RCOR; COREST; KIAA0071
UniProt Protein Name
REST corepressor 1
UniProt Synonym Protein Names
Protein CoREST
Protein Family
UniProt Gene Name
RCOR1
UniProt Synonym Gene Names
KIAA0071; RCOR
UniProt Entry Name
RCOR1_HUMAN
NCBI Protein Information
REST corepressor 1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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