Mouse Anti-SLC27A2 Monoclonal Antibody – Cat# MBS6144420

Detection limit for recombinant GST tagged SLC27A2 is 1ng/ml as a capture antibody.

SLC27A2 Antibody – Mouse Monoclonal

Name: SLC27A2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6144420
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6144420

MBS6144420 is an antibody targeting SLC27A2. Also known as SLC27A2 (Solute Carrier Family 27 Member 2, ACSVL1, Fatty Acid Transport Protein 2, FATP2, FATP-2, Fatty-acid-coenzyme A Ligase, Very Long-chain 1, FACVL1, Long-chain-fatty-acid--CoA Ligase, THCA-CoA… More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC27A2, Monoclonal Antibody

Full Product Name

SLC27A2 (Solute Carrier Family 27 Member 2, ACSVL1, Fatty Acid Transport Protein 2, FATP2, FATP-2, Fatty-acid-coenzyme A Ligase, Very Long-chain 1, FACVL1, Long-chain-fatty-acid--CoA Ligase, THCA-CoA Ligase, Very Long-chain-fatty-acid-CoA Ligase, Very Lon

Product Gene Name

anti-SLC27A2 antibody

Product Synonym Names

EC=6.2.1.-; EC=6.2.1.3; hFACVL1; HsT17226

Clonality

Monoclonal

Isotype

IgG2a,k

Clone Number

1F1

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human SLC27A2.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

70kDa

OMIM

603247

3D Structure

ModBase 3D Structure for O14975

Immunogen

Partial recombinant corresponding to aa25-124 from human SLC27A2 (NP_003636) with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

YFFQDIGYFLKVAAVGRRVRSYGQRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLG

Conjugate

Biotin

Product Categories/Family for anti-SLC27A2 antibody

Antibodies; Ion Channel

Applications Tested/Suitable for anti-SLC27A2 antibody

ELISA (EIA)

Application Notes for anti-SLC27A2 antibody

ELISA: 1ng/ml
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-SLC27A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC27A2. It may not necessarily be applicable to this product.

NCBI GI #

227499619

NCBI GeneID

11001

NCBI Accession #

NP_003636

UniProt Primary Accession #

O14975

UniProt Related Accession #

O14975

GenBank Nucleotide #

NM_003645

NCBI Official Full Name

very long-chain acyl-CoA synthetase isoform 1

NCBI Official Synonym Full Names

solute carrier family 27 member 2

NCBI Official Symbol

SLC27A2

NCBI Official Synonym Symbols

VLCS; FATP2; VLACS; ACSVL1; FACVL1; hFACVL1; HsT17226

UniProt Protein Name

Very long-chain acyl-CoA synthetase

UniProt Synonym Protein Names

Fatty acid transport protein 2; FATP-2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain-fatty-acid--CoA ligase (EC:6.2.1.3); Solute carrier family 27 member 2; THCA-CoA ligase; Very long-chain-fatty-acid-CoA ligase

Protein Family

Very long-chain acyl-CoA synthetase

UniProt Gene Name

SLC27A2

UniProt Synonym Gene Names

ACSVL1; FACVL1; FATP2; VLACS; VLACS; VLCS; FATP-2

UniProt Entry Name

S27A2_HUMAN

NCBI Protein Information

very long-chain acyl-CoA synthetase

NCBI Summary for SLC27A2

The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

UniProt Comments for SLC27A2

SLC27A2: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes. Belongs to the ATP-dependent AMP-binding enzyme family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; EC 6.2.1.3; Membrane protein, integral; Ligase

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: peroxisomal membrane; integral to peroxisomal membrane; endoplasmic reticulum membrane; mitochondrion; endoplasmic reticulum lumen; integral to endoplasmic reticulum membrane

Molecular Function: enzyme binding; fatty acid transporter activity; very-long-chain-fatty-acid-CoA ligase activity; phytanate-CoA ligase activity; ATP binding; receptor binding; long-chain-fatty-acid-CoA ligase activity

Biological Process: bile acid biosynthetic process; fatty acid beta-oxidation; very-long-chain fatty acid catabolic process; bile acid metabolic process; cellular lipid metabolic process; long-chain fatty acid metabolic process; fatty acid alpha-oxidation

Research Articles on SLC27A2

1. In overweight/obese pregnancies, the increased FATP2 placental expression could contribute to increased fatty acid delivery to the fetus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.