• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

UBE4B Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6145041

MBS6145041 is an antibody targeting UBE4B. Also known as UBE4B (Ubiquitin Conjugation Factor E4 B, Homozygously Deleted in Neuroblastoma 1, HDNB1, KIAA0684, Ubiquitin Fusion Degradation Protein 2, UFD2) (Biotin). Reactive in Human. Host: Mouse. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UBE4B, Monoclonal Antibody
Full Product Name
UBE4B (Ubiquitin Conjugation Factor E4 B, Homozygously Deleted in Neuroblastoma 1, HDNB1, KIAA0684, Ubiquitin Fusion Degradation Protein 2, UFD2) (Biotin)
Product Gene Name
Product Synonym Names
E4; UBOX3; UFD2A
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
8F9
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human UBE4B.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
OMIM
613565
3D Structure
ModBase 3D Structure for O95155
Immunogen
Partial recombinant corresponding to aa1075-1173 from UBE4B (NP_006039) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
FKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILRHLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH
Conjugate
Biotin

Product Categories/Family for anti-UBE4B antibody

Applications Tested/Suitable for anti-UBE4B antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-UBE4B antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-UBE4B antibody

Western Blot detection against Immunogen (37kD).
Mouse Anti-UBE4B Monoclonal Antibody – Cat# MBS6145041

Testing Data of anti-UBE4B antibody

UBE4B monoclonal antibody Blot analysis of UBE4B expression in HeLa NE
Mouse Anti-UBE4B Monoclonal Antibody, Testing Data – Cat# MBS6145041

Other Notes

Small volumes of anti-UBE4B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UBE4B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Homo sapiens ubiquitination factor E4B (UBE4B), transcript variant 2, mRNA
NCBI Official Synonym Full Names
ubiquitination factor E4B
NCBI Official Symbol
UBE4B
NCBI Official Synonym Symbols
E4; UFD2; HDNB1; UBOX3; UFD2A
UniProt Protein Name
Ubiquitin conjugation factor E4 B
UniProt Synonym Protein Names
Homozygously deleted in neuroblastoma 1; Ubiquitin fusion degradation protein 2
UniProt Gene Name
UBE4B
UniProt Entry Name
UBE4B_HUMAN
NCBI Protein Information
ubiquitin conjugation factor E4 B

NCBI Summary for UBE4B

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for UBE4B

UBE4B: Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3. Belongs to the ubiquitin conjugation factor E4 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ligase; EC 6.3.2.19; EC 6.3.2.-; Ubiquitin conjugating system; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 1p36.3

Cellular Component: cytoplasm; nucleus; ubiquitin ligase complex

Molecular Function: enzyme binding; ligase activity

Biological Process: proteasomal ubiquitin-dependent protein catabolic process; induction of apoptosis by granzyme; protein ubiquitination during ubiquitin-dependent protein catabolic process; response to UV
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000