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CLDN5 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6146540

Plays a major role in tight junction-specific obliteration of the intercellular space. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLDN5, Monoclonal Antibody
Full Product Name
CLDN5 (Claudin-5, Transmembrane Protein Deleted in VCFS, TMDVCF, AWAL, TMVCF, BEC1, CPETRL1) (FITC)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
3D8
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human CLDN5.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
23kDa
OMIM
602101
3D Structure
ModBase 3D Structure for O00501
Immunogen
Partial recombinant protein corresponding to aa29-81 from human CLDN5 with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAAR*
Conjugate
FITC

Product Categories/Family for anti-CLDN5 antibody

Applications Tested/Suitable for anti-CLDN5 antibody
FLISA
Application Notes for anti-CLDN5 antibody
Applications are based on unconjugated antibody.

Testing Data of anti-CLDN5 antibody

Detection limit for recombinant GST tagged CLDN5 is ~0.1ng/ml as a capture antibody.
Mouse Anti-CLDN5 Monoclonal Antibody – Cat# MBS6146540

Other Notes

Small volumes of anti-CLDN5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLDN5 purchase

MBS6146540 is an antibody targeting CLDN5. Also known as CLDN5 (Claudin-5, Transmembrane Protein Deleted in VCFS, TMDVCF, AWAL, TMVCF, BEC1, CPETRL1) (FITC). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CLDN5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
claudin-5 isoform 1
NCBI Official Synonym Full Names
claudin 5
NCBI Official Symbol
CLDN5
NCBI Official Synonym Symbols
AWAL; BEC1; TMVCF; TMDVCF; CPETRL1
UniProt Protein Name
Claudin-5
UniProt Synonym Protein Names
Transmembrane protein deleted in VCFS
Protein Family
UniProt Gene Name
CLDN5
UniProt Synonym Gene Names
AWAL; TMVCF; TMDVCF
UniProt Entry Name
CLD5_HUMAN
NCBI Protein Information
claudin-5

NCBI Summary for CLDN5

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]
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UniProt Comments for CLDN5

Claudin-5: Plays a major role in tight junction-specific obliteration of the intercellular space. Belongs to the claudin family.

Protein type: Cytoskeletal; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: tight junction; integral to membrane; plasma membrane; intercellular junction

Molecular Function: identical protein binding; structural molecule activity

Biological Process: calcium-independent cell-cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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