Mouse Anti-PCNT1 Monoclonal Antibody – Cat# MBS6148597

Pericentrin 1 (PCNT1) Antibody – Mouse Monoclonal

Name: PCNT1 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6148597
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6148597

NUP85 (Nucleoporin 85; also Nup75/nucleoporin 75 and FROUNT) is a 70-72kD member of the nucleoporin Nup85 family of proteins. It is one of nine members of the Nup107-160 subcomplex that performs at least two functions in the cell. First, it serves as an… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pericentrin 1 (PCNT1), Monoclonal Antibody

Full Product Name

Pericentrin 1 (Pericentrin-1, PCNT1, FLJ12549, Frount, Frount Protein, Kendrin, KEN, Nucleoporin 85, Nucleoporin-85, Nucleoporin 85kDa, NUP85, Nucleoporin Nup75, Nup75, Pericentrin, PCN, PCNT) (FITC)

Product Gene Name

anti-PCNT1 antibody

Clonality

Monoclonal

Isotype

IgG2b,k

Clone Number

3E9

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).

Purity/Purification

Purified by Protein A Affinity Chromatography.

Specificity

Recognizes human NUP85.

Preparation and Storage

Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

69,800 Da

Immunogen

Full length recombinant corresponding to aa1-657 from human NUP85 (AAH00697) with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

MEELDGEPTVTLIPGVNSKKNQMYFDWGPGEMLVCETSFNKKEKSEMVPSCPFIYIIRKDVDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRACMEEMHQVAIAAKDPANGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHDSFWNLVTILVLQGRLDEARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQDSTFATSPHLESLLKIMLGDEAALLEQKELLSNWYHFLVTRLLYSNPTVKPIDLHYYAQSSLDLFLGGESSPEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHPSLWQLGVDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARAIIREGSLEGS

Conjugate

FITC

Product Categories/Family for anti-PCNT1 antibody

Antibodies; Mitosis Proteins

Applications Tested/Suitable for anti-PCNT1 antibody

ELISA (EIA)

Application Notes for anti-PCNT1 antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-PCNT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PCNT1 purchase

MBS6148597 is an antibody targeting PCNT1. Also known as Pericentrin 1 (Pericentrin-1, PCNT1, FLJ12549, Frount, Frount Protein, Kendrin, KEN, Nucleoporin 85, Nucleoporin-85, Nucleoporin 85kDa, NUP85, Nucleoporin Nup75, Nup75, Pericentrin, PCN, PCNT) (FITC). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PCNT1. It may not necessarily be applicable to this product.

NCBI GI #

33990865

NCBI GeneID

79902

NCBI Accession #

BC000697

NCBI Related Accession #

AAH00697

UniProt Secondary Accession #

Q8NDI4; Q9H9U1; B4DMQ3; B4DPW1

UniProt Related Accession #

Q9BW27

NCBI Official Full Name

Homo sapiens nucleoporin 85kDa, mRNA

NCBI Official Synonym Full Names

nucleoporin 85

NCBI Official Symbol

NUP85

NCBI Official Synonym Symbols

Nup75; FROUNT

Protein Family

Nuclear pore complex protein

NCBI Protein Information

nuclear pore complex protein Nup85

NCBI Summary for PCNT1

This gene encodes a protein component of the Nup107-160 subunit of the nuclear pore complex. Nuclear pore complexes are embedded in the nuclear envelope and promote bidirectional transport of macromolecules between the cytoplasm and nucleus. The encoded protein can also bind to the C-terminus of chemokine (C-C motif) receptor 2 (CCR2) and promote chemotaxis of monocytes, thereby participating in the inflammatory response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Research Articles on PCNT1

1. results support a model of CCR2 equilibrium: chemokine binding changes the conformational equilibrium of CCR2 toward the active state, and Pro-C switches its binding partner from the membrane to FROUNT

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PCNT1 antibody

Products by Pathway	Pathway Diagram
Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies	Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Export Of Viral Ribonucleoproteins From Nucleus Pathway antibodies	Export Of Viral Ribonucleoproteins From Nucleus Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Glucose Transport Pathway antibodies	Glucose Transport Pathway Diagram
HIV Infection Pathway antibodies	HIV Infection Pathway Diagram
HIV Life Cycle Pathway antibodies	HIV Life Cycle Pathway Diagram

Diseases associated with anti-PCNT1 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>2 publications with PCNT1 and Inflammation
Cardiovascular Diseases Antibodies	>1 publications with PCNT1 and Cardiovascular Diseases
Prostatic Diseases Antibodies	>1 publications with PCNT1 and Prostatic Diseases
Neoplasms Antibodies	>1 publications with PCNT1 and Neoplasms

Organs/Tissues associated with anti-PCNT1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>2 publications with PCNT1 and Blood
Bone Marrow Antibodies	>2 publications with PCNT1 and Bone Marrow
Bone Antibodies	>2 publications with PCNT1 and Bone
Heart Antibodies	>1 publications with PCNT1 and Heart
Vascular Antibodies	>1 publications with PCNT1 and Vascular
Prostate Antibodies	>1 publications with PCNT1 and Prostate