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PAX9 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6148688

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PAX9, Monoclonal Antibody
Full Product Name
PAX9 (Paired Box Protein Pax-9) (FITC)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
4B9
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human PAX9. Species Crossreactivity: rat.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
38.7 kDa (364aa)
OMIM
167416
3D Structure
ModBase 3D Structure for P55771
Immunogen
Full length recombinant corresponding to aa205-300 from human PAX9 (NP_006185) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
RSITDQVSDSSPYHSPKVEEWSSLGRNNFPAAAPHAVNGLEKGALEQEAKYGQAPNGLPAVGSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGH
Conjugate
FITC
Applications Tested/Suitable for anti-PAX9 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PAX9 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PAX9 antibody

Western Blot detection against Immunogen (36.56kD).
Mouse Anti-PAX9 Monoclonal Antibody – Cat# MBS6148688

Western Blot (WB) of anti-PAX9 antibody

PAX9 monoclonal antibody. Western Blot analysis of PAX9 expression in PC-12.
Mouse Anti-PAX9 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6148688

Western Blot (WB) of anti-PAX9 antibody

PAX9 monoclonal antibody Western Blot analysis of PAX9 expression in Hela NE.
Mouse Anti-PAX9 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6148688

Western Blot (WB) of anti-PAX9 antibody

Western Blot analysis of PAX9 expression in transfected 293T cell line by PAX9 monoclonal antibody. Lane 1: PAX9 transfected lysate (36.3kD). Lane 2: Non-transfected lysate.
Mouse Anti-PAX9 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6148688

Western Blot (WB) of anti-PAX9 antibody

Western blot analysis of PAX9 over-expressed 293 cell line, cotransfected with PAX9 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with PAX9 monoclonal antibody GAPDH (36.1kD) used as specificity and loading control.
Mouse Anti-PAX9 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6148688

Other Notes

Small volumes of anti-PAX9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAX9 purchase

MBS6148688 is an antibody targeting PAX9. Also known as PAX9 (Paired Box Protein Pax-9) (FITC). Reactive in Human, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PAX9. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
paired box protein Pax-9
NCBI Official Synonym Full Names
paired box 9
NCBI Official Symbol
PAX9
NCBI Official Synonym Symbols
STHAG3
UniProt Protein Name
Paired box protein Pax-9
Protein Family
UniProt Gene Name
PAX9
UniProt Entry Name
PAX9_HUMAN
NCBI Protein Information
paired box protein Pax-9

NCBI Summary for PAX9

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. Mice lacking this gene exhibit impaired development of organs, musculature and the skeleton, including absent and abnormally developed teeth, and neonatal lethality. Mutations in the human gene are associated with selective tooth agenesis-3. [provided by RefSeq, Sep 2015]
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UniProt Comments for PAX9

PAX9: Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs. Interacts with KDM5B.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 14q13.3

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: odontogenesis; transcription, DNA-dependent; regulation of odontogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; endoderm development

Disease: Tooth Agenesis, Selective, 3
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PAX9 antibody

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