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PCBD1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6148696

PCBD1 encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PCBD1, Monoclonal Antibody
Full Product Name
PCBD1 (DCOH, PCBD, Pterin-4-alpha-carbinolamine Dehydratase, 4-alpha-hydroxy-tetrahydropterin Dehydratase, Dimerization Cofactor of Hepatocyte Nuclear Factor 1-alpha, Phenylalanine Hydroxylase-stimulating Protein, Pterin Carbinolamine Dehydratase) (FITC)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1G11-H5
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human PCBD1.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
12,000 Da
Immunogen
Full length recombinant corresponding to aa1-105 from human PCBD1 (AAH06324) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MAGKAHRLSAEERDQLLPNLRAVGWNELEGRDAIFKQFHFKDFNRAFGFMTRVALQAEKLDHHPEWFNVYNKVHITLSTHECAGLSERDINLASFIEQVAVSMT
Conjugate
FITC

Product Categories/Family for anti-PCBD1 antibody

Applications Tested/Suitable for anti-PCBD1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PCBD1 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PCBD1 antibody

Western Blot detection against Immunogen (37.18kD).
Mouse Anti-PCBD1 Monoclonal Antibody – Cat# MBS6148696

Western Blot (WB) of anti-PCBD1 antibody

Western Blot analysis using MBS6002490 for PCBD1 expression in C32.
Mouse Anti-PCBD1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6148696

Other Notes

Small volumes of anti-PCBD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PCBD1 purchase

MBS6148696 is an antibody targeting PCBD1. Also known as PCBD1 (DCOH, PCBD, Pterin-4-alpha-carbinolamine Dehydratase, 4-alpha-hydroxy-tetrahydropterin Dehydratase, Dimerization Cofactor of Hepatocyte Nuclear Factor 1-alpha, Phenylalanine Hydroxylase-stimulating Protein, Pterin Carbinolamine Dehydratase) (FITC). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PCBD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha, mRNA
NCBI Official Synonym Full Names
pterin-4 alpha-carbinolamine dehydratase 1
NCBI Official Symbol
PCBD1
NCBI Official Synonym Symbols
PCD; PHS; DCOH; PCBD
NCBI Protein Information
pterin-4-alpha-carbinolamine dehydratase

NCBI Summary for PCBD1

This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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