Rabbit Anti-FOXK2 Polyclonal Antibody – Cat# MBS614922

Isoform 3 (FOXK2) Antibody – Rabbit Polyclonal

Name: FOXK2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS614922
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS614922

MBS614922 is an antibody targeting FOXK2. Also known as FOXK2, Isoform 3 (Forkhead Box K2, Cellular Transcription Factor ILF-1, Interleukin Enhancer-Binding Factor 1). Reactive in Human. Host: Rabbit. More details

$305 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FOXK2, Isoform 3, Polyclonal Antibody

Full Product Name

FOXK2, Isoform 3 (Forkhead Box K2, Cellular Transcription Factor ILF-1, Interleukin Enhancer-Binding Factor 1)

Product Gene Name

anti-FOXK2 antibody

Product Synonym Names

Anti -FOXK2, Isoform 3 (Forkhead Box K2, Cellular Transcription Factor ILF-1, Interleukin Enhancer-Binding Factor 1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, sodium azide, before the addition of glycerol to 40%.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human FOXK2, Isoform 3.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

69,062 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (80477594..80562483). Location: 17q25

OMIM

147685

3D Structure

ModBase 3D Structure for Q01167

Immunogen

Synthetic peptide QRGESFAHVGNTRIR of human FOXK2 (KLH).

Product Categories/Family for anti-FOXK2 antibody

Antibodies; Abs to Transcription Factors

Applications Tested/Suitable for anti-FOXK2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-FOXK2 antibody

Suitable for use in ELISA and Western Blot.
Dilution: ELISA Titer: 1:250,000.
Western Blot: 1ug/ml. A band is detected at 32kD using Ramos.

Other Notes

Small volumes of anti-FOXK2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FOXK2. It may not necessarily be applicable to this product.

NCBI GI #

119610206

NCBI GeneID

3607

UniProt Primary Accession #

Q01167

UniProt Secondary Accession #

Q13622; Q13623; Q13624; A6NEP5

UniProt Related Accession #

Q01167; Q9H0E4

NCBI Official Full Name

forkhead box K2, isoform CRA_a

NCBI Official Synonym Full Names

forkhead box K2

NCBI Official Symbol

FOXK2

NCBI Official Synonym Symbols

ILF; ILF1; ILF-1

UniProt Protein Name

Forkhead box protein K2

UniProt Synonym Protein Names

Cellular transcription factor ILF-1; FOXK1; Interleukin enhancer-binding factor 1

Protein Family

Forkhead box protein

UniProt Gene Name

FOXK2

UniProt Synonym Gene Names

ILF; ILF1

UniProt Entry Name

FOXK2_HUMAN

NCBI Protein Information

forkhead box protein K2; FOXK1; OTTHUMP00000179134; OTTHUMP00000233365; cellular transcription factor ILF-1; interleukin enhancer binding factor 1; interleukin enhancer-binding factor 1

NCBI Summary for FOXK2

The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. [provided by RefSeq]

UniProt Comments for FOXK2

FOXK2: Recognizes the core sequence 5'-TAAACA-3'. Binds to NFAT-like motifs (purine-rich) in the IL2 promoter. Also binds to HIV-1 long terminal repeat. May be involved in both positive and negative regulation of important viral and cellular promoter elements. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 17q25

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; magnesium ion binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter

Research Articles on FOXK2

1. Data show that FOXK2 is subject to control by cell cycle-regulated hyperphosphorylation occurring in CDK).cyclin-dependent manner with CDK1.cyclin B as the major kinase complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-FOXK2 antibody

Disease Name	Pubmed Publications
Esophageal Neoplasms Antibodies	>1 publications with FOXK2 and Esophageal Neoplasms
Cell Transformation, Neoplastic Antibodies	>1 publications with FOXK2 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-FOXK2 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with FOXK2 and Lung
Brain Antibodies	>1 publications with FOXK2 and Brain