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Splicing Factor, Arginine/Serine-Rich 12 (SREK1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS614954

MBS614954 is an antibody targeting SREK1. Also known as Splicing Factor, Arginine/Serine-Rich 12 (SFRS12, Serine/Arginine-Rich Splicing Regulatory Protein 86, SRrp86, Splicing Regulatory Protein 508, SRrp508). Reactive in Human, Rodent. Host: Rabbit. More details

$365 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Splicing Factor, Arginine/Serine-Rich 12 (SREK1), Polyclonal Antibody
Full Product Name
Splicing Factor, Arginine/Serine-Rich 12 (SFRS12, Serine/Arginine-Rich Splicing Regulatory Protein 86, SRrp86, Splicing Regulatory Protein 508, SRrp508)
Product Gene Name
Product Synonym Names
Anti -Splicing Factor, Arginine/Serine-Rich 12 (SFRS12, Serine/Arginine-Rich Splicing Regulatory Protein 86, SRrp86, Splicing Regulatory Protein 508, SRrp508)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rodent
Form/Format
Supplied as a liquid in PBS, pH 7.2, 40% glycerol.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human Splicing Factor, Arginine/Serine-Rich 12.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
59,380 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (65440046..65479444). Location: 5q12.3
OMIM
609268
3D Structure
ModBase 3D Structure for Q8WXA9
Immunogen
Synthetic peptide aa409-424, PRSRNKKDKKREKERD of human SFRS12 (KLH). MW: 59,380kD.
Applications Tested/Suitable for anti-SREK1 antibody
ELISA (EL/EIA), Immunohistochemistry (IHC)
Application Notes for anti-SREK1 antibody
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA (serum titer): 1:1375,000
Western Blot: Preliminary results: MCF7 cells 110kD, Human breast 70kD (Weak)
Immunohistochemistry: 5ug/ml

Other Notes

Small volumes of anti-SREK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SREK1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
splicing regulatory glutamine/lysine-rich protein 1 isoform c
NCBI Official Synonym Full Names
splicing regulatory glutamine/lysine-rich protein 1
NCBI Official Symbol
SREK1
NCBI Official Synonym Symbols
SFRS12; SRrp86; SRrp508
UniProt Protein Name
Splicing regulatory glutamine/lysine-rich protein 1
UniProt Synonym Protein Names
Serine/arginine-rich-splicing regulatory protein 86; SRrp86; Splicing factor, arginine/serine-rich 12; Splicing regulatory protein 508
UniProt Gene Name
SREK1
UniProt Synonym Gene Names
SFRS12; SRRP86; SRrp86; SRrp508
UniProt Entry Name
SREK1_HUMAN
NCBI Protein Information
splicing regulatory glutamine/lysine-rich protein 1; splicing regulatory protein 508; splicing factor, arginine/serine-rich 12; serine/arginine-rich-splicing regulatory protein 86; serine-arginine-rich splicing regulatory protein 508

NCBI Summary for SREK1

This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
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UniProt Comments for SREK1

SFRS12: Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA splicing; RNA processing

Chromosomal Location of Human Ortholog: 5q12.3

Cellular Component: nucleoplasm; spliceosome

Molecular Function: nucleotide binding

Biological Process: RNA splicing; mRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SREK1 antibody

 Reference Product  PubMed Publications
 SRSF3 antibody  >2 publications with SREK1 and SRSF3

Pathways associated with anti-SREK1 antibody

 Products by Pathway  Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram

Organs/Tissues associated with anti-SREK1 antibody

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