M1-M4 Nuclear Ribonucleoprotein, Nrnp, Hnrnp) (RNP) Antibody – Human Polyclonal

Heterogeneous nuclear ribonucleoproteins (hnRNP) bind to nascent RNA polymerase II transcripts and are involved in transcript-specific packaging as well as alternative splicing of pre-mRNAs. hnRNPs also appear to influence mRNA metabolism and transport. In vivo, the M proteins bind to mRNA, and in vitro they bind avidly to poly(G) and poly(U) homopolymers. Four different isoforms of hnRNP are produced by alternative splicing: M1, M2, M3, and M4. Ongoing studies have theorized that hnRNPs may cause certain genetic diseases such as myotonic dystrophy, which is the most common form of adult muscular dystrophy. The identification of hnRNPs may therefore be important to determining the cause and cure for genetic diseases.

Delipidized and defibrinated gamma fraction from a single donor.

Small volumes of anti-RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS614994 is an antibody targeting RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP). Reactive in Human. Host: Human.