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KIAA1598 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS615114

The differentiation process of neurons can be divided into five stages, each stage characterized by morphological changes observed in the developing cells. In stage 1, the cells extend lamellipodia and in stage 2 their lamellipodia develop into immature… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Shootin1 (KIAA1598), Polyclonal Antibody
Full Product Name
Shootin1
Product Gene Name
Product Synonym Names
Anti -Shootin1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100ug/ml BSA and 50% glycerol.
Purity/Purification
Affinity Purified
Purified by peptide affinity chromatography.
Specificity
Detects endogenous levels of total shootin1 protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
71,640 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (118644306..118765088, complement). Location: 10q25.3
OMIM
611171
3D Structure
ModBase 3D Structure for A0MZ66
Immunogen
Synthetic peptide (KLH-coupled) surrounding Lys450 of human shootin1.
Applications Tested/Suitable for anti-KIAA1598 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-KIAA1598 antibody
Suitable for use in Western Blot and Immunoprecipitation.
Dilution: Western Blot: 1:1000
Immunoprecipitation: 1:100

Western Blot (WB) of anti-KIAA1598 antibody

Western blot analysis of extracts from neonatal mouse and fetal rat brain using MBS615114
Rabbit Anti-KIAA1598 Polyclonal Antibody – Cat# MBS615114

Other Notes

Small volumes of anti-KIAA1598 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KIAA1598 purchase

MBS615114 is an antibody targeting KIAA1598. Also known as Shootin1. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KIAA1598. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
shootin-1 isoform a
NCBI Official Synonym Full Names
KIAA1598
NCBI Official Symbol
KIAA1598
NCBI Official Synonym Symbols
MGC40476; SHOOTIN1; shootin-1; DKFZp686A0439
UniProt Protein Name
Shootin-1
UniProt Gene Name
KIAA1598
UniProt Entry Name
SHOT1_HUMAN
NCBI Protein Information
shootin-1; shootin1; OTTHUMP00000020573

UniProt Comments for KIAA1598

SHOT1: Involved in the generation of internal asymmetric signals required for neuronal polarization. Acts upstream of PI3K (phosphoinositide 3-kinase), by being required for spatially localized PI3K activity. Accumulates asymmetrically in a single neurite before polarization, leading to axon induction for polarization, its absence from the nascent axon's siblings by competition preventing the formation of surplus axons. Interacts with RUFY3. Belongs to the shootin family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 10q25.3

Molecular Function: kinase binding

Biological Process: axon guidance
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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