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FAAH Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6152424

Endogenous cannabinoids have been implicated in addictive behaviors and drug abuse. Fatty-acid amide hydrolase 1 (FAAH1) is a plasma membrane-bound hydrolase that converts oleamide to oleic acid. This hydrolase also converts the cannabinoid anandamide, the… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
FAAH, Monoclonal Antibody
Full Product Name
FAAH (Fatty-acid Amide Hydrolase 1, Anandamide Amidohydrolase 1, Oleamide Hydrolase 1, FAAH1, MGC102823, MGC138146) (HRP)
Product Gene Name
anti-FAAH antibody
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2G8
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human FAAH. Species Crossreactivity: rat.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
63,066 Da
OMIM
gene 606581
3D Structure
ModBase 3D Structure for O00519
Immunogen
Partial recombinant corresponding to aa480-579 from human FAAH (NP_001432) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
DLNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMKKSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
Conjugate
HRP

Product Categories/Family for anti-FAAH antibody

Antibodies; Enzymes
Applications Tested/Suitable for anti-FAAH antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-FAAH antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-FAAH antibody

Western Blot detection against Immunogen (36.74kD).
Mouse Anti-FAAH Monoclonal Antibody – Cat# MBS6152424

Western Blot (WB) of anti-FAAH antibody

FAAH monoclonal antibody. Western Blot analysis of FAAH expression in rat muscle.
Mouse Anti-FAAH Monoclonal Antibody, Western Blot (WB) – Cat# MBS6152424

Western Blot (WB) of anti-FAAH antibody

FAAH monoclonal antibody. Western Blot analysis of FAAH expression in MCF-7.
Mouse Anti-FAAH Monoclonal Antibody, Western Blot (WB) – Cat# MBS6152424

Testing Data of anti-FAAH antibody

Detection limit for recombinant GST tagged FAAH is ~0.3ng/ml as a capture antibody.
Mouse Anti-FAAH Monoclonal Antibody, Testing Data – Cat# MBS6152424

Other Notes

Small volumes of anti-FAAH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FAAH purchase

MBS6152424 is an antibody targeting FAAH. Also known as FAAH (Fatty-acid Amide Hydrolase 1, Anandamide Amidohydrolase 1, Oleamide Hydrolase 1, FAAH1, MGC102823, MGC138146) (HRP). Reactive in Human, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FAAH. It may not necessarily be applicable to this product.

NCBI GI #
166795287
NCBI GeneID
2166
NCBI Accession #
NP_001432
UniProt Primary Accession #
O00519
UniProt Secondary Accession #
Q52M86; Q5TDF8; D3DQ19
UniProt Related Accession #
O00519
GenBank Nucleotide #
NM_001441
NCBI Official Full Name
fatty-acid amide hydrolase 1
NCBI Official Synonym Full Names
fatty acid amide hydrolase
NCBI Official Symbol
FAAH
NCBI Official Synonym Symbols
PSAB; FAAH-1
UniProt Protein Name
Fatty-acid amide hydrolase 1
UniProt Synonym Protein Names
Anandamide amidohydrolase 1; Oleamide hydrolase 1
Protein Family
Fatty acid amide hydrolase
UniProt Gene Name
FAAH
UniProt Synonym Gene Names
FAAH1
UniProt Entry Name
FAAH1_HUMAN
NCBI Protein Information
fatty-acid amide hydrolase 1; anandamide amidohydrolase 1; oleamide hydrolase 1

UniProt Comments for FAAH

FAAH: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. Homodimer. Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate. Inhibited by O-aryl carbamates and alpha-keto heterocytes. Belongs to the amidase family.

Protein type: EC 3.5.1.99; Membrane protein, integral; Hydrolase

Chromosomal Location of Human Ortholog: 1p35-p34

Cellular Component: cytoskeleton; cytoplasm; integral to membrane; endomembrane system

Molecular Function: fatty acid amide hydrolase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor; acylglycerol lipase activity

Biological Process: fatty acid catabolic process

Disease: Polysubstance Abuse, Susceptibility To
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FAAH antibody

 Reference Product  PubMed Publications
 TRPV1 antibody  >93 publications with FAAH and TRPV1
 CNR1 antibody  >40 publications with FAAH and CNR1
 CNR2 antibody  >16 publications with FAAH and CNR2
 MGLL antibody  >9 publications with FAAH and MGLL
 FABP5 antibody  >4 publications with FAAH and FABP5
 NAPEPLD antibody  >3 publications with FAAH and NAPEPLD
 FABP7 antibody  >3 publications with FAAH and FABP7
 FABP3 antibody  >2 publications with FAAH and FABP3
 LEP antibody  >1 publications with FAAH and LEP

Pathways associated with anti-FAAH antibody

 Products by Pathway  Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Retrograde Endocannabinoid Signaling Pathway antibodies  Retrograde Endocannabinoid Signaling Pathway Diagram
 Anandamide Degradation Pathway antibodies  Anandamide Degradation Pathway Diagram
 Anandamide Degradation Pathway antibodies  Anandamide Degradation Pathway Diagram

Diseases associated with anti-FAAH antibody

 Disease Name  Pubmed Publications
 Pain Antibodies  >195 publications with FAAH and Pain
 Nervous System Diseases Antibodies  >149 publications with FAAH and Nervous System Diseases
 Inflammation Antibodies  >91 publications with FAAH and Inflammation
 Mental Disorders Antibodies  >89 publications with FAAH and Mental Disorders
 Obesity Antibodies  >53 publications with FAAH and Obesity
 Fatty Liver Antibodies  >52 publications with FAAH and Fatty Liver
 Substance-Related Disorders Antibodies  >46 publications with FAAH and Substance-Related Disorders
 Brain Diseases Antibodies  >44 publications with FAAH and Brain Diseases
 Death Antibodies  >22 publications with FAAH and Death
 Necrosis Antibodies  >19 publications with FAAH and Necrosis

Organs/Tissues associated with anti-FAAH antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >398 publications with FAAH and Brain
 Nerve Antibodies  >48 publications with FAAH and Nerve
 Muscle Antibodies  >32 publications with FAAH and Muscle
 Intestine Antibodies  >30 publications with FAAH and Intestine
 Adipose Tissue Antibodies  >25 publications with FAAH and Adipose Tissue
 Connective Tissue Antibodies  >20 publications with FAAH and Connective Tissue
 Eye Antibodies  >19 publications with FAAH and Eye
 Placenta Antibodies  >15 publications with FAAH and Placenta
 Lung Antibodies  >14 publications with FAAH and Lung
 Kidney Antibodies  >12 publications with FAAH and Kidney
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