• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

FVT1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6152590

FVT1 catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving its gene is a cause… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FVT1, Monoclonal Antibody
Full Product Name
FVT1 (Follicular Variant Translocation Protein 1, FVT-1, 3-dehydrosphinganine Reductase, DHSR, 3-ketodihydrosphingosine Reductase, KDS Reductase, KDSR, FLJ36555, FLJ92680, SDR35C1) (HRP)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2B2-3C11
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human FVT1.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
29,159 Da
Immunogen
Full length recombinant corresponding to aa1-332 from human FVT1 (AAH08797.1) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
FVLLLYMVSPLISPKPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTSVCKPEQVAKQIVKDAIQGNFNSSLGSDGYMLSALTCGMAPVTSITEGLQQVVTMGLFRTIALFYLGSFDSIVRRCMMQREKSENADKTA
Conjugate
HRP

Product Categories/Family for anti-FVT1 antibody

Applications Tested/Suitable for anti-FVT1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-FVT1 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-FVT1 antibody

Western Blot detection against Immunogen (61.05kD).
Mouse Anti-FVT1 Monoclonal Antibody – Cat# MBS6152590

Western Blot (WB) of anti-FVT1 antibody

FVT1 monoclonal antibody, Western Blot analysis of FVT1 expression in Jurkat.
Mouse Anti-FVT1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6152590

Testing Data of anti-FVT1 antibody

Detection limit for recombinant GST tagged FVT1 is ~1ng/ml as a capture antibody.
Mouse Anti-FVT1 Monoclonal Antibody, Testing Data – Cat# MBS6152590

Other Notes

Small volumes of anti-FVT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FVT1 purchase

MBS6152590 is an antibody targeting FVT1. Also known as FVT1 (Follicular Variant Translocation Protein 1, FVT-1, 3-dehydrosphinganine Reductase, DHSR, 3-ketodihydrosphingosine Reductase, KDS Reductase, KDSR, FLJ36555, FLJ92680, SDR35C1) (HRP). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FVT1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens 3-ketodihydrosphingosine reductase, mRNA
NCBI Official Synonym Full Names
3-ketodihydrosphingosine reductase
NCBI Official Symbol
KDSR
NCBI Official Synonym Symbols
DHSR; FVT1; SDR35C1
NCBI Protein Information
3-ketodihydrosphingosine reductase; 3-dehydrosphinganine reductase; FVT-1; KDS reductase; follicular lymphoma variant translocation 1; follicular variant translocation protein 1; short chain dehydrogenase/reductase family 35C, member 1

NCBI Summary for FVT1

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008]
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000