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Cerebellin Precursor (CBLN1) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS615293

Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q (1). Cerebellin exerts neuromodulatory functions by directly stimulating… More details

$850 / 0.1 mg +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
Cerebellin Precursor (CBLN1), Polyclonal Antibody
Full Product Name
Cerebellin Precursor, CT (Cbln1, Precerebellin)
Product Gene Name
Product Synonym Names
Anti -Cerebellin Precursor, CT (Cbln1, Precerebellin)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human precerebellin. Species Crossreactivity: mouse and rat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
21,097 Da
Chromosome Location
Chromosome: 16; NC_000016.9 (49311828..49315742, complement). Location: 16q12.1
OMIM
600432
3D Structure
ModBase 3D Structure for P23435
Immunogen
Synthetic peptide corresponding to 16aa near the carboxy- terminus of human precerebellin (Genbank accession No. P23435).

Product Categories/Family for anti-CBLN1 antibody

Applications Tested/Suitable for anti-CBLN1 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes for anti-CBLN1 antibody
Suitable for use in Western Blot and Immunocytochemistry.
Dilution: Western Blot: 2-4ug/ml
Immunocytochemistry: 10ug/ml

Western Blot (WB) of anti-CBLN1 antibody

Western Blot analysis of precerebellin in 293 cell lysate with MBS615293 at (A) 2ug/ml and (B) 4ug/ml.
Rabbit Anti-CBLN1 Polyclonal Antibody – Cat# MBS615293

Immunohistochemistry (IHC) of anti-CBLN1 antibody

Immunohistochemistry of precerebellin in 3T3 cells with MBS615293 at 10ug/ml.
Rabbit Anti-CBLN1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS615293

Other Notes

Small volumes of anti-CBLN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CBLN1 purchase

MBS615293 is an antibody targeting CBLN1. Also known as Cerebellin Precursor, CT (Cbln1, Precerebellin). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CBLN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cerebellin-1
NCBI Official Synonym Full Names
cerebellin 1 precursor
NCBI Official Symbol
CBLN1
UniProt Protein Name
Cerebellin-1
UniProt Synonym Protein Names
Precerebellin
Protein Family
UniProt Gene Name
CBLN1
UniProt Entry Name
CBLN1_HUMAN
NCBI Protein Information
cerebellin-1; precerebellin; OTTHUMP00000164195

NCBI Summary for CBLN1

This gene encodes a cerebellum-specific precursor protein, precerebellin, with similarity to the globular (non-collagen-like) domain of complement component C1qB. Precerebellin is processed to give rise to several derivatives, including the hexadecapeptide, cerebellin, which is highly enriched in postsynaptic structures of Purkinje cells. Cerebellin has also been found in human and rat adrenals, where it has been shown to enhance the secretory activity of this gland. [provided by RefSeq]
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UniProt Comments for CBLN1

CBLN1: Cerebellin-1 is required for synapse integrity and synaptic plasticity. Required for the ER export and secretion of CBLN3.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q12.1

Cellular Component: postsynaptic membrane; extracellular region; cell junction

Molecular Function: protein homodimerization activity

Biological Process: heterophilic cell adhesion; nervous system development; positive regulation of synaptogenesis; synaptic transmission; protein secretion; cerebellar granule cell differentiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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