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HOXB7 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6152938

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HOXB7, Monoclonal Antibody
Full Product Name
HOXB7 (HOX2C, Homeobox Protein Hox-B7, Homeobox Protein HHO.C1, Homeobox Protein Hox-2C) (HRP)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
5B2
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human HOXB7.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
24kDa
OMIM
142962
3D Structure
ModBase 3D Structure for P09629
Immunogen
Partial recombinant corresponding to aa55-120 from human HOXB7 (NP_004493) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAA
Conjugate
HRP
Applications Tested/Suitable for anti-HOXB7 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-HOXB7 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-HOXB7 antibody

Western Blot detection against Immunogen (33kD).
Mouse Anti-HOXB7 Monoclonal Antibody – Cat# MBS6152938

Western Blot (WB) of anti-HOXB7 antibody

Western Blot analysis of HOXB7 expression in transfected 293T cell line by HOXB7 monoclonal antibody. Lane 1: HOXB7 transfected lysate (24kD). Lane 2: Non-transfected lysate.
Mouse Anti-HOXB7 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6152938

Testing Data of anti-HOXB7 antibody

Detection limit for recombinant GST tagged HOXB7 is ~0.1ng/ml as a capture antibody.
Mouse Anti-HOXB7 Monoclonal Antibody, Testing Data – Cat# MBS6152938

Western Blot (WB) of anti-HOXB7 antibody

Western blot analysis of HOXB7 over-expressed 293 cell line, cotransfected with HOXB7 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with HOXB7 monoclonal antibody GAPDH (36.1kD) used as specificity and loading control.
Mouse Anti-HOXB7 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6152938

Other Notes

Small volumes of anti-HOXB7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HOXB7 purchase

MBS6152938 is an antibody targeting HOXB7. Also known as HOXB7 (HOX2C, Homeobox Protein Hox-B7, Homeobox Protein HHO.C1, Homeobox Protein Hox-2C) (HRP). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for HOXB7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
homeobox protein Hox-B7
NCBI Official Synonym Full Names
homeobox B7
NCBI Official Symbol
HOXB7
NCBI Official Synonym Symbols
HOX2; HOX2C; HHO.C1; Hox-2.3
UniProt Protein Name
Homeobox protein Hox-B7
UniProt Synonym Protein Names
Homeobox protein HHO.C1; Homeobox protein Hox-2C
Protein Family
UniProt Gene Name
HOXB7
UniProt Synonym Gene Names
HOX2C
UniProt Entry Name
HXB7_HUMAN
NCBI Protein Information
homeobox protein Hox-B7

NCBI Summary for HOXB7

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]
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UniProt Comments for HOXB7

HOXB7: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family.

Protein type: Motility/polarity/chemotaxis; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription factor activity

Biological Process: anterior/posterior pattern formation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development; myeloid cell differentiation; embryonic skeletal morphogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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