SLC32A1 Antibody – Rabbit Polyclonal

Classical neurotransmitters are synthesized in the cytoplasm, and so must be transported into synaptic vesicles for regulated exocytosis of vesicles filled with neurotransmitter. Although the vesicular transporters for monoamines and acetylcholine have been identified, the proteins responsible for packaging the primary inhibitory and excitatory transmitters, gamma aminobutyric acid (GABA) and glutamate have only recently been identified. Studies in the nematode Caenorhabditis elegans have implicated the gene unc-47 in the release of GABA. Recently, rat homolog of unc-47 have been cloned and characterized. Rat VGAT, a 525 aa membrane protein with ten transmembrane domains, is expressed by central GABA neurons. Both N and C-termini are predicted to be cytoplasmic. Rat VGAT and unc-47 share ~38% sequence identity. Rat VGAT is primarily expressed in the brain

Small volumes of anti-SLC32A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS615406 is an antibody targeting SLC32A1. Also known as VGAT (solute carrier family 32 (GABA vesicular transporter) member 1, GABA and glycine transporter, SLC32A 1, Solute carrier family 32 member 1, VGAT, VIAAT, Vesicular GABA Amino Acid Transporter, Vesicular GABA transporter, Vesicular inhibitory amino aci. Reactive in Rat. Host: Rabbit.