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EIF3S2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6157601

EIF3S2 is the largest of the EIFs. It consists of at least 10 nonidentical subunits in mammals. In S. cerevisiae the p39 subunit contains WD repeats; these are thought to mediate protein-protein interactions. The p39 protein appears to be essential for… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EIF3S2, Monoclonal Antibody
Full Product Name
EIF3S2 (Eukaryotic Translation Initiation Factor 3 Subunit I, eIF3i, Eukaryotic Translation Initiation Factor 3 Subunit 2, eIF-3-beta, eIF3 p36, TGF-beta Receptor-Interacting Protein 1, TRIP-1, TRIP1, EIF3I) (PE)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3B10
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human EIF3S2.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
603911
3D Structure
ModBase 3D Structure for Q13347
Immunogen
Partial recombinant corresponding to aa226-326 from EIF3S2 (NP_003748) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
FRTERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTRIGKFEARFFHLAFEEEFGRVKGHFGPINSVAFHPDGKSYSSGGEDGYVRIHYFDPQYFEFEFEA*
Conjugate
PE
Applications Tested/Suitable for anti-EIF3S2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-EIF3S2 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-EIF3S2 antibody

Western Blot detection against Immunogen (37.11kD).
Mouse Anti-EIF3S2 Monoclonal Antibody – Cat# MBS6157601

Testing Data of anti-EIF3S2 antibody

Detection limit for recombinant GST tagged EIF3I is 1ng/ml as a capture antibody.
Mouse Anti-EIF3S2 Monoclonal Antibody, Testing Data – Cat# MBS6157601

Other Notes

Small volumes of anti-EIF3S2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EIF3S2 purchase

MBS6157601 is an antibody targeting EIF3S2. Also known as EIF3S2 (Eukaryotic Translation Initiation Factor 3 Subunit I, eIF3i, Eukaryotic Translation Initiation Factor 3 Subunit 2, eIF-3-beta, eIF3 p36, TGF-beta Receptor-Interacting Protein 1, TRIP-1, TRIP1, EIF3I) (PE). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF3S2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
eukaryotic translation initiation factor 3 subunit I
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 3 subunit I
NCBI Official Symbol
EIF3I
NCBI Official Synonym Symbols
TRIP1; EIF3S2; TRIP-1; PRO2242; eIF3-p36; eIF3-beta
UniProt Protein Name
Eukaryotic translation initiation factor 3 subunit I
UniProt Synonym Protein Names
Eukaryotic translation initiation factor 3 subunit 2; TGF-beta receptor-interacting protein 1; eIF3 p36
UniProt Gene Name
EIF3I
UniProt Entry Name
EIF3I_HUMAN
NCBI Protein Information
eukaryotic translation initiation factor 3 subunit I

UniProt Comments for EIF3S2

eIF3-beta: eukaryotic translation initiation factor 3 subunit 2. Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. eIF-3 is composed of at least 12 different subunits. Phosphorylated by TGF-beta type II receptor.

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: eukaryotic translation initiation factor 3 complex; cytosol

Molecular Function: protein binding; translation initiation factor activity

Biological Process: cellular protein metabolic process; translation; translational initiation; gene expression; formation of translation preinitiation complex; regulation of translational initiation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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