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Groucho 3 (gro) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS615920

MBS615920 is an antibody targeting gro. Also known as Groucho 3 (TLE3, ESG3, Transcription Factor). Reactive in Human, Rodent. Host: Rabbit. More details

$365 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Groucho 3, Polyclonal Antibody
Full Product Name
Groucho 3 (TLE3, ESG3, Transcription Factor)
Product Gene Name
Product Synonym Names
Anti -Groucho 3 (TLE3, ESG3, Transcription Factor)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rodent
Form/Format
Supplied as a liquid in PBS, sodium azide, before the addition of glycerol to 40%.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Specificity
Recognizes human Groucho 3 / TLE3 / ESG3 transcription factor. Species Crossreactivity: rodent.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer
Molecular Weight
83.4kD.
Chromosome Location
Chromosome: 3R; NT_033777.2 (21867458..21875633). Location: 96F10-96F10; 3-89.1 cM
3D Structure
ModBase 3D Structure for P16371
Immunogen
Synthetic peptide, aa 295-311 STPSSKTKDLGHNDKKSS corresponding to human Groucho 3 (KLH).
Applications Tested/Suitable for anti-gro antibody
ELISA (EL/EIA)
Application Notes for anti-gro antibody
Suitable for use in ELISA.
Dilution: ELISA (titer): 1:200,000.

Other Notes

Small volumes of anti-gro antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for gro. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
groucho, isoform I
NCBI Official Synonym Full Names
groucho
NCBI Official Symbol
gro
NCBI Official Synonym Symbols
anon-WO0118547.385; BcDNA.LD33829; BcDNA:LD33829; BEST:GM01575; BEST:LD15161; CG8384; dAES1; dAES2; dGro; DGro; DmelCG8384; E(spl)-WD; E(spl)gro; E(spl)m9/m10; E(spl)[2]; En-spl; Grg/TLE; Gro; GRO; Groucho; l(3)gro; m10; m9; m9-m10; m9/10; m9/m10
UniProt Protein Name
Protein groucho
UniProt Synonym Protein Names
Enhancer of split m9/10 protein
Protein Family
UniProt Gene Name
gro
UniProt Synonym Gene Names
E(spl)m9/m10; E(spl)m9/10
UniProt Entry Name
GROU_DROME
NCBI Protein Information
CG8384 gene product from transcript CG8384-RH; CG8384-PA; CG8384-PB; CG8384-PC; CG8384-PD; CG8384-PE; CG8384-PF; CG8384-PG; CG8384-PH; CG8384-PI; dgroucho; gro-PA; gro-PB; gro-PC; gro-PD; gro-PE; gro-PF; gro-PG; gro-PH; gro-PI

UniProt Comments for gro

Function: Transcriptional corepressor that regulates transcription when recruited to specific target DNA by hairy-related bHLH proteins. Maternally required for neurogenesis; in the segregation of the neuroectoderm. Directly or indirectly interacts with Notch and Delta. Ref.5

Subunit structure: Forms a complex with the hairy/Enhancer of split/deadpan family of basic helix-loop-helix proteins in order to repress transcription. Its activity in regulating transcription depends on other proteins as it lacks a DNA-binding motif.

Subcellular location: Nucleus.

Developmental stage: Expressed both maternally and zygotically. Ref.5

Post-translational modification: Ubiquitinated by XIAP/BIRC4. Ref.7

Sequence similarities: Belongs to the WD repeat Groucho/TLE family.Contains 7 WD repeats.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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