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PSENEN Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6159693

MBS6159693 is an antibody targeting PSENEN. Also known as PSENEN (Presenilin Enhancer Protein 2, PEN2, Gamma-secretase Subunit PEN-2, MDS033, MSTP064) (PE). Reactive in Human. Host: Mouse. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PSENEN, Monoclonal Antibody
Full Product Name
PSENEN (Presenilin Enhancer Protein 2, PEN2, Gamma-secretase Subunit PEN-2, MDS033, MSTP064) (PE)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1C12-G5
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human PSENEN.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
12,029 Da
Immunogen
Full length recombinant corresponding to aa1-102 from human PSENEN (AAH09575) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MNLERVSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFREAFLVPAYTEQSQIKGYVWRSAVGFLFWVIVLTSWITIFQIYRPRWGALGDYLSFTIPLGTP
Conjugate
PE

Product Categories/Family for anti-PSENEN antibody

Applications Tested/Suitable for anti-PSENEN antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PSENEN antibody
ELISA: 0.1ng/ml
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PSENEN antibody

Western Blot detection against Immunogen (37.22kD).
Mouse Anti-PSENEN Monoclonal Antibody – Cat# MBS6159693

Testing Data of anti-PSENEN antibody

Detection limit for recombinant GST tagged PSENEN is ~0.1ng/ml as a capture antibody.
Mouse Anti-PSENEN Monoclonal Antibody, Testing Data – Cat# MBS6159693

Other Notes

Small volumes of anti-PSENEN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PSENEN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens presenilin enhancer 2 homolog (C. elegans), mRNA
NCBI Official Synonym Full Names
presenilin enhancer gamma-secretase subunit
NCBI Official Symbol
PSENEN
NCBI Official Synonym Symbols
PEN2; PEN-2; MDS033; MSTP064
Protein Family
NCBI Protein Information
gamma-secretase subunit PEN-2

NCBI Summary for PSENEN

Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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