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PSMA8 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6159698

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PSMA8, Monoclonal Antibody
Full Product Name
PSMA8 (Proteasome Subunit alpha Type-7-like, PSMA7L, MGC26605) (PE)
Product Gene Name
anti-PSMA8 antibody
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
2E3
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human PSMA8. Species Crossreactivity: mouse and rat.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
28kDa
3D Structure
ModBase 3D Structure for Q8TAA3
Immunogen
Partial recombinant protein corresponding to aa143-243 from human PSMA8 (NP_653263) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
GFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIASDSEAIKLAIKALLEVVQSGGRNIELAIIRRNQPLKMFSAKEVELYVTEIEK
Conjugate
PE

Product Categories/Family for anti-PSMA8 antibody

Antibodies; Proteasomes
Applications Tested/Suitable for anti-PSMA8 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PSMA8 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PSMA8 antibody

Western Blot detection against Immunogen (37.11kD).
Mouse Anti-PSMA8 Monoclonal Antibody – Cat# MBS6159698

Western Blot (WB) of anti-PSMA8 antibody

PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in PC-12.
Mouse Anti-PSMA8 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6159698

Western Blot (WB) of anti-PSMA8 antibody

PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in Jurkat.
Mouse Anti-PSMA8 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6159698

Western Blot (WB) of anti-PSMA8 antibody

PSMA8 monoclonal antibody. Western Blot analysis of PSMA8 expression in NIH/3T3.
Mouse Anti-PSMA8 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6159698

Western Blot (WB) of anti-PSMA8 antibody

PSMA8 monoclonal antibody, Western Blot analysis of PSMA8 expression in K-562.
Mouse Anti-PSMA8 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6159698

Other Notes

Small volumes of anti-PSMA8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSMA8 purchase

MBS6159698 is an antibody targeting PSMA8. Also known as PSMA8 (Proteasome Subunit alpha Type-7-like, PSMA7L, MGC26605) (PE). Reactive in Human, Mouse, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMA8. It may not necessarily be applicable to this product.

NCBI GI #
68303561
NCBI GeneID
143471
NCBI Accession #
NP_653263
UniProt Primary Accession #
Q8TAA3
UniProt Related Accession #
Q8TAA3
GenBank Nucleotide #
NM_144662
NCBI Official Full Name
proteasome subunit alpha-type 8 isoform 1
NCBI Official Synonym Full Names
proteasome subunit alpha 8
NCBI Official Symbol
PSMA8
NCBI Official Synonym Symbols
PSMA7L
UniProt Protein Name
Proteasome subunit alpha type-7-like
Protein Family
Proteasome
UniProt Gene Name
PSMA8
UniProt Synonym Gene Names
PSMA7L
UniProt Entry Name
PSA7L_HUMAN
NCBI Protein Information
proteasome subunit alpha-type 8; proteasome subunit alpha type-7-like

UniProt Comments for PSMA8

PSMA8: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This may be a testis-specific subunit. Belongs to the peptidase T1A family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.25.1; Protease; Proteasome complex

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: nucleus; cytosol

Molecular Function: threonine endopeptidase activity

Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; negative regulation of apoptosis
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Research Articles on PSMA8

1. This article provides an overview of some of the components in the human 20 S proteasome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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