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RAB6A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6159787

MBS6159787 is an antibody targeting RAB6A. Also known as RAB6A (Ras-related Protein Rab-6A, Rab-6, RAB6) (PE). Reactive in Human, Rat. Host: Mouse. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAB6A, Monoclonal Antibody
Full Product Name
RAB6A (Ras-related Protein Rab-6A, Rab-6, RAB6) (PE)
Product Gene Name
anti-RAB6A antibody
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
3G3
Host
Mouse
Species Reactivity
Human, Rat
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human RAB6A. Species Crossreactivity: rat.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
19,935 Da
Immunogen
Partial recombinant corresponding to aa109-208, from human RAB6A (AAH03617) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
DDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC
Conjugate
PE

Product Categories/Family for anti-RAB6A antibody

Antibodies; GTPase; Rab; Ras; Rho Proteins
Applications Tested/Suitable for anti-RAB6A antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-RAB6A antibody
IHC-P: 3ug/ml
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-RAB6A antibody

RAB6A monoclonal antibody. Western Blot analysis of RAB6A expression in PC-12.
Mouse Anti-RAB6A Monoclonal Antibody – Cat# MBS6159787

Western Blot (WB) of anti-RAB6A antibody

RAB6A monoclonal antibody. Western Blot analysis of RAB6A expression in HL-60.
Mouse Anti-RAB6A Monoclonal Antibody, Western Blot (WB) – Cat# MBS6159787

Immunohistochemistry (IHC) of anti-RAB6A antibody

Immunoperoxidase of monoclonal antibody to RAB6A on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3ug/ml]
Mouse Anti-RAB6A Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6159787

Testing Data of anti-RAB6A antibody

Detection limit for recombinant GST tagged RAB6A is ~1ng/ml as a capture antibody.
Mouse Anti-RAB6A Monoclonal Antibody, Testing Data – Cat# MBS6159787

Other Notes

Small volumes of anti-RAB6A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB6A. It may not necessarily be applicable to this product.

NCBI GI #
33870607
NCBI GeneID
5870
NCBI Accession #
BC003617
NCBI Related Accession #
AAH03617
UniProt Secondary Accession #
Q1W5D8; Q5U0A8; Q9UBE4; A8K133; B7Z772; F5H668
UniProt Related Accession #
P20340
NCBI Official Full Name
Homo sapiens RAB6A, member RAS oncogene family, mRNA
NCBI Official Synonym Full Names
RAB6A, member RAS oncogene family
NCBI Official Symbol
RAB6A
NCBI Official Synonym Symbols
RAB6
Protein Family
Ras-related protein
NCBI Protein Information
ras-related protein Rab-6A

NCBI Summary for RAB6A

This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
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Research Articles on RAB6A

1. Rab6A binding to KIF1C's motor domain represents an entirely new mode of regulation for a kinesin motor, and likely has important consequences for KIF1C's cellular functions.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-RAB6A antibody

 Products by Pathway  Pathway Diagram
 Pre-NOTCH Expression And Processing Pathway antibodies  Pre-NOTCH Expression And Processing Pathway Diagram
 Pre-NOTCH Processing In Golgi Pathway antibodies  Pre-NOTCH Processing In Golgi Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By NOTCH Pathway antibodies  Signaling By NOTCH Pathway Diagram

Diseases associated with anti-RAB6A antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with RAB6A and Neoplasms
 Brain Diseases Antibodies  >1 publications with RAB6A and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with RAB6A and Kidney Diseases
 Necrosis Antibodies  >1 publications with RAB6A and Necrosis

Organs/Tissues associated with anti-RAB6A antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with RAB6A and Brain
 Kidney Antibodies  >1 publications with RAB6A and Kidney
 Prostate Antibodies  >1 publications with RAB6A and Prostate
 Eye Antibodies  >1 publications with RAB6A and Eye
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