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SERPINB3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6160203

May act as a protease inhibitor to modulate the host immune response against tumor cells. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SERPINB3, Monoclonal Antibody
Full Product Name
SERPINB3 (Serpin B3, Protein T4-A, Squamous Cell Carcinoma Antigen 1, SCCA-1, SCCA, SCCA1) (PE)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2F5
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human SERPINB3.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
47kDa (413aa) confirmed by MALDI-TOF
OMIM
600517
3D Structure
ModBase 3D Structure for P29508
Immunogen
Partial recombinant corresponding to aa276-391 from human SERPINB3 (NP_008850) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
RETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP*
Conjugate
PE
Applications Tested/Suitable for anti-SERPINB3 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-SERPINB3 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-SERPINB3 antibody

Western Blot detection against Immunogen (38.76kD).
Mouse Anti-SERPINB3 Monoclonal Antibody – Cat# MBS6160203

Western Blot (WB) of anti-SERPINB3 antibody

Western Blot analysis of SERPINB3 expression in transfected 293T cell line by SERPINB3 monoclonal antibody. Lane 1: SERPINB3 transfected lysate (44.6kD). Lane 2: Non-transfected lysate.
Mouse Anti-SERPINB3 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6160203

Immunoprecipitation (IP) of anti-SERPINB3 antibody

Immunoprecipitation of SERPINB3 transfected lysate using SERPINB3 monoclonal antibody and Protein A Magnetic Bead and immunoblotted with SERPINB3 rabbit polyclonal antibody.
Mouse Anti-SERPINB3 Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS6160203

Testing Data of anti-SERPINB3 antibody

Detection limit for recombinant GST tagged SERPINB3 is ~0.3ng/ml as a capture antibody.
Mouse Anti-SERPINB3 Monoclonal Antibody, Testing Data – Cat# MBS6160203

Other Notes

Small volumes of anti-SERPINB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SERPINB3 purchase

MBS6160203 is an antibody targeting SERPINB3. Also known as SERPINB3 (Serpin B3, Protein T4-A, Squamous Cell Carcinoma Antigen 1, SCCA-1, SCCA, SCCA1) (PE). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINB3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
serpin B3
NCBI Official Synonym Full Names
serpin family B member 3
NCBI Official Symbol
SERPINB3
NCBI Official Synonym Symbols
SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD
UniProt Protein Name
Serpin B3
UniProt Synonym Protein Names
Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1
Protein Family
UniProt Gene Name
SERPINB3
UniProt Synonym Gene Names
SCCA; SCCA1; SCCA-1
UniProt Entry Name
SPB3_HUMAN
NCBI Protein Information
serpin B3

UniProt Comments for SERPINB3

SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular space; nucleus; vesicle

Molecular Function: cysteine protease inhibitor activity; protease binding; serine-type endopeptidase inhibitor activity; viral receptor activity

Biological Process: negative regulation of catalytic activity; negative regulation of JNK activity; negative regulation of peptidase activity; negative regulation of proteolysis; positive regulation of cell migration; positive regulation of cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SERPINB3 antibody

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