Mouse Anti-RAB11FIP3 Monoclonal Antibody – Cat# MBS6165727

Detection limit for recombinant GST tagged RAB11FIP3 is 0.03 ng/ml as a capture antibody.

RAB11FIP3 Antibody – Mouse Monoclonal

Name: RAB11FIP3 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS6165727
Price: 995 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6165727

Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al.,… More details

$995 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAB11FIP3, Monoclonal Antibody

Full Product Name

RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II), KIAA0665, Rab11-FIP3) (AP)

Product Gene Name

anti-RAB11FIP3 antibody

Product Synonym Names

RAB11 Family Interacting Protein 3 (Class II); KIAA0665; Rab11-FIP3

Clonality

Monoclonal

Isotype

IgG2a,k

Clone Number

6H6

Host

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

Purity/Purification

Purified

Specificity

Recognizes RAB11FIP3.

Preparation and Storage

Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

OMIM

608738

3D Structure

ModBase 3D Structure for O75154

Immunogen

RAB11FIP3 (NP_055515.1, 655aa-754aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.

Immunogen Sequence

HSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAIMETNPSILE

Conjugate

Product Categories/Family for anti-RAB11FIP3 antibody

Antibodies; GTPase; Rab; Ras; Rho Proteins

Applications Tested/Suitable for anti-RAB11FIP3 antibody

Western Blot (WB)

Application Notes for anti-RAB11FIP3 antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-RAB11FIP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB11FIP3 purchase

MBS6165727 is an antibody targeting RAB11FIP3. Also known as RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II), KIAA0665, Rab11-FIP3) (AP). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB11FIP3. It may not necessarily be applicable to this product.

NCBI GI #

7662234

NCBI GeneID

9727

NCBI Accession #

NP_055515.1

UniProt Primary Accession #

O75154

UniProt Related Accession #

O75154

GenBank Nucleotide #

NP_055515.1

NCBI Official Full Name

rab11 family-interacting protein 3 isoform 1

NCBI Official Synonym Full Names

RAB11 family interacting protein 3

NCBI Official Symbol

RAB11FIP3

NCBI Official Synonym Symbols

CART1; FIP3-Rab11; Rab11-FIP3

UniProt Protein Name

Rab11 family-interacting protein 3

UniProt Synonym Protein Names

Arfophilin-1; EF hands-containing Rab-interacting protein; Eferin; MU-MB-17.148

Protein Family

Rab11 family-interacting protein

UniProt Gene Name

RAB11FIP3

UniProt Synonym Gene Names

ARFO1; KIAA0665; FIP3-Rab11; Rab11-FIP3; Eferin

UniProt Entry Name

RFIP3_HUMAN

NCBI Protein Information

rab11 family-interacting protein 3

UniProt Comments for RAB11FIP3

RAB11FIP3: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: nucleoplasm; centrosome; recycling endosome; intercellular bridge; intracellular membrane-bound organelle; recycling endosome membrane; microtubule organizing center; midbody; cytosol; endosome; cleavage furrow

Molecular Function: ADP-ribosylation factor binding; protein binding; protein homodimerization activity; calcium ion binding; Rab GTPase binding

Biological Process: vesicle-mediated transport; organelle organization and biogenesis; cytokinesis; endocytic recycling

Research Articles on RAB11FIP3

1. Rac1-Rab11-FIP3 regulatory hub coordinates vesicle traffic with actin remodeling and T-cell activation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.