Mouse Anti-NKX2-5 Monoclonal Antibody – Cat# MBS6166537

Detection limit for recombinant GST tagged NKX2-5 is approximately 0.1ng/ml as a capture antibody.

NKX2-5 Antibody – Mouse Monoclonal

Name: NKX2-5 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS6166537
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6166537

Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been… More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NKX2-5, Monoclonal Antibody

Full Product Name

NKX2-5 (NK2 Transcription Factor Related, locus 5 (Drosophila), CHNG5, CSX, CSX1, NKX2.5, NKX2E, NKX4-1) (APC)

Product Gene Name

anti-NKX2-5 antibody

Product Synonym Names

NK2 Transcription Factor Related; locus 5 (Drosophila); CHNG5; CSX; CSX1; NKX2.5; NKX2E; NKX4-1

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

Host

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Purity/Purification

Purified

Specificity

Recognizes NKX2-5.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Immunogen

NKX2-5 (AAH25711, 1aa-324aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.

Conjugate

APC

Product Categories/Family for anti-NKX2-5 antibody

Antibodies; Transcription Factors

Applications Tested/Suitable for anti-NKX2-5 antibody

Western Blot (WB)

Application Notes for anti-NKX2-5 antibody

Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-NKX2-5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NKX2-5 purchase

MBS6166537 is an antibody targeting NKX2-5. Also known as NKX2-5 (NK2 Transcription Factor Related, locus 5 (Drosophila), CHNG5, CSX, CSX1, NKX2.5, NKX2E, NKX4-1) (APC). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for NKX2-5. It may not necessarily be applicable to this product.

NCBI GI #

19343931

NCBI GeneID

1482

NCBI Accession #

AAH25711

UniProt Related Accession #

P52952

NCBI Official Full Name

NK2 transcription factor related, locus 5 (Drosophila)

NCBI Official Synonym Full Names

NK2 homeobox 5

NCBI Official Symbol

NKX2-5

NCBI Official Synonym Symbols

CSX; CSX1; VSD3; CHNG5; HLHS2; NKX2E; NKX2.5; NKX4-1

Protein Family

Homeobox protein

NCBI Protein Information

homeobox protein Nkx-2.5

NCBI Summary for NKX2-5

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Research Articles on NKX2-5

1. Nkx2.5 acts upstream of GDF1 and the genetic variants in GDF1 promoter may confer genetic susceptibility to sporadic CHD potentially by altering its expression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.