Galanin (GAL) Antibody – Rabbit Polyclonal

Galanin is a 29 aa C-terminally amidated (30 aa, non-amidated in humans), highly conserved but unique neuroendocrine peptide originally isolated from intestine. The first 14 aa are fully conserved in almost all species. Galanin is found in the brain and the gut. It modulates a variety of physiological processed including cognition/memory, sensory/pain processing, neurotransmitter/hormone secretion, and feeding behavior. Several N-terminally elongated (-7-29 and -9-29) or truncated biologically active forms of galanin have also been isolated. Galanin antagonists are chimeric peptides generated by linking the amino terminal portion of galanin to substance P (galantide, M15), bradykinin (M35), the neurokinin antagonist spantide (C7) or an idealized alpha helical region (M40) (see review in refs 2 by Kask et al 1995).

• 1. Tatemoto K et al (1983) FEBS Lett. 164, 124-128;
• 2. Vrontakis ME et al (1987) J Biol. Chem. 272, 16755-16758 ;
• 3. Rokaeus A and Carlquist M (1988) FEBS Lett. 234, 400-406;
• 4. Bersani et al (1991) FEBS Lett. 283, 189-194;
• 5. Sillard R et al (1991) Peptides 12, 855-859;
• 6. Wang Y and Conlon JM (1994) Peptides 15, 981-986.
• 7. Melander T et al (1986) J Comp. Neurol. 248, 475-517;
• 8. Melander T et al (1986) Neuroscience 19, 223-240;
• 9. Skofitch G and Jacobwitz DM et al (1986) Peptides 6, 509-546;
• 10. ibid (1986) Peptides 7, 609-613; 11. Kask K et al (1995) Cell Mol Neurobiol. 15, 653-674 (review).

Small volumes of anti-GAL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS616721 is an antibody targeting GAL. Also known as Anti - Galanin. Reactive in Human. Host: Rabbit
Source: Human.