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USF2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6167284

This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two… More details

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Product Overview

Online Datasheet in PDF
Product Name
USF2, Monoclonal Antibody
Full Product Name
USF2 (Upstream Transcription Factor 2, c-fos Interacting, FIP, bHLHb12) (APC)
Product Gene Name
anti-USF2 antibody
Product Synonym Names
Upstream Transcription Factor 2; c-fos Interacting; FIP; bHLHb12
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
5F2
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified
Specificity
Recognizes USF2.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
37kDa
OMIM
600390
3D Structure
ModBase 3D Structure for Q15853
Immunogen
USF2 (NP_003358, 1aa-100aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Conjugate
APC

Product Categories/Family for anti-USF2 antibody

Antibodies; Transcription Factors
Applications Tested/Suitable for anti-USF2 antibody
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-USF2 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-USF2 antibody

USF2 monoclonal antibody (M02), clone 5F2. Western Blot analysis of USF2 expression in Hela S3 NE.
Mouse Anti-USF2 Monoclonal Antibody – Cat# MBS6167284

Western Blot (WB) of anti-USF2 antibody

USF2 monoclonal antibody (M02), clone 5F2. Western Blot analysis of USF2 expression in different cell lines.
Mouse Anti-USF2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6167284

Immunofluorescence (IF) of anti-USF2 antibody

Immunofluorescence of monoclonal antibody to USF2 on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-USF2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6167284

Immunofluorescence (IF) of anti-USF2 antibody

Immunofluorescence of monoclonal antibody to USF2 on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-USF2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6167284

Immunohistochemistry (IHC) of anti-USF2 antibody

Immunoperoxidase of monoclonal antibody to USF2 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 1 ug/ml]
Mouse Anti-USF2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6167284

Immunohistochemistry (IHC) of anti-USF2 antibody

Immunoperoxidase of monoclonal antibody to USF2 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 1 ug/ml]
Mouse Anti-USF2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6167284

Other Notes

Small volumes of anti-USF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for USF2 purchase

MBS6167284 is an antibody targeting USF2. Also known as USF2 (Upstream Transcription Factor 2, c-fos Interacting, FIP, bHLHb12) (APC). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for USF2. It may not necessarily be applicable to this product.

NCBI GI #
4507847
NCBI GeneID
7392
NCBI Accession #
NP_003358
UniProt Primary Accession #
Q15853
UniProt Related Accession #
Q15853
GenBank Nucleotide #
NM_003367
NCBI Official Full Name
upstream stimulatory factor 2 isoform 1
NCBI Official Synonym Full Names
upstream transcription factor 2, c-fos interacting
NCBI Official Symbol
USF2
NCBI Official Synonym Symbols
FIP; bHLHb12
UniProt Protein Name
Upstream stimulatory factor 2
UniProt Synonym Protein Names
Class B basic helix-loop-helix protein 12; bHLHb12; FOS-interacting protein; FIP; Major late transcription factor 2; Upstream transcription factor 2
Protein Family
Upstream stimulatory factor
UniProt Gene Name
USF2
UniProt Synonym Gene Names
BHLHB12; bHLHb12; FIP
UniProt Entry Name
USF2_HUMAN
NCBI Protein Information
upstream stimulatory factor 2

NCBI Summary for USF2

This gene encodes a member of the basic helix-loop-helix leucine zipper family of transcription factors. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes. [provided by RefSeq, Mar 2016]
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UniProt Comments for USF2

USF2: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: nucleoplasm; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein homodimerization activity; sequence-specific DNA binding; protein heterodimerization activity; double-stranded DNA binding; bHLH transcription factor binding; transcription factor activity

Biological Process: lactation; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter by glucose; lipid homeostasis; late viral mRNA transcription; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter by glucose
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Research Articles on USF2

1. TCF21 modulates Steroidogenic factor-1 and estrogen receptor beta expression through the recruitment of USF2 in endometriotic stromal cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-USF2 antibody

 Reference Product  PubMed Publications
 USF1 antibody  >166 publications with USF2 and USF1
 FOS antibody  >7 publications with USF2 and FOS
 MAF antibody  >2 publications with USF2 and MAF
 EP300 antibody  >2 publications with USF2 and EP300
 IGF2R antibody  >1 publications with USF2 and IGF2R
 BRCA1 antibody  >1 publications with USF2 and BRCA1

Pathways associated with anti-USF2 antibody

 Products by Pathway  Pathway Diagram
 Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway antibodies  Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway Diagram

Diseases associated with anti-USF2 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >38 publications with USF2 and Neoplasms
 Kidney Diseases Antibodies  >10 publications with USF2 and Kidney Diseases
 Liver Diseases Antibodies  >9 publications with USF2 and Liver Diseases
 Fatty Liver Antibodies  >8 publications with USF2 and Fatty Liver
 Inflammation Antibodies  >7 publications with USF2 and Inflammation
 Breast Neoplasms Antibodies  >6 publications with USF2 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >6 publications with USF2 and Carcinoma, Hepatocellular
 Fibrosis Antibodies  >5 publications with USF2 and Fibrosis
 Cell Transformation, Neoplastic Antibodies  >5 publications with USF2 and Cell Transformation, Neoplastic
 Congenital Abnormalities Antibodies  >4 publications with USF2 and Congenital Abnormalities

Organs/Tissues associated with anti-USF2 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >38 publications with USF2 and Liver
 Blood Antibodies  >23 publications with USF2 and Blood
 Kidney Antibodies  >18 publications with USF2 and Kidney
 Brain Antibodies  >14 publications with USF2 and Brain
 Lung Antibodies  >12 publications with USF2 and Lung
 Testis Antibodies  >9 publications with USF2 and Testis
 Ovary Antibodies  >8 publications with USF2 and Ovary
 Heart Antibodies  >8 publications with USF2 and Heart
 Pancreas Antibodies  >8 publications with USF2 and Pancreas
 Adipose Tissue Antibodies  >7 publications with USF2 and Adipose Tissue
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