Mouse Anti-SQSTM1 Monoclonal Antibody – Cat# MBS6168223

Detection limit for recombinant GST tagged SQSTM1 is approximately 3ng/ml as a capture antibody.

SQSTM1 Antibody – Mouse Monoclonal

Name: SQSTM1 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS6168223
Price: 1140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6168223

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to… More details

$1140 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SQSTM1, Monoclonal Antibody

Full Product Name

SQSTM1 (sequestosome 1, A170, OSIL, PDB3, ZIP3, p60, p62, p62B) (APC)

Product Gene Name

anti-SQSTM1 antibody

Product Synonym Names

sequestosome 1; A170; OSIL; PDB3; ZIP3; p60; p62; p62B

Clonality

Monoclonal

Isotype

IgG3,k

Clone Number

1C9

Host

Mouse

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Purity/Purification

Purified

Specificity

Recognizes SQSTM1.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Immunogen

SQSTM1 (AAH03139.1, 1aa-440aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.

Conjugate

APC

Product Categories/Family for anti-SQSTM1 antibody

Antibodies; Ubiquitin

Applications Tested/Suitable for anti-SQSTM1 antibody

Western Blot (WB)

Application Notes for anti-SQSTM1 antibody

Applications are based on unconjugated antibody.

Product References and Citations for anti-SQSTM1 antibody

1. Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation.Notte A, Ninane N, Arnould T, Michiels CCell Death Dis. 2013 May 16;4:e638. doi: 10.1038/cddis.2013.167. 2.BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway. Cosse JP, Rommelaere G, Ninane N, Arnould T, Michiels C.Biochem Pharmacol. 2010 Jul 15. 3.A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates.Kirkin V, Lamark T, Sou YS, Bjorkoy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Overvatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T.Mol Cell. 2009 Feb 27;33(4):505-16.

Other Notes

Small volumes of anti-SQSTM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SQSTM1 purchase

MBS6168223 is an antibody targeting SQSTM1. Also known as SQSTM1 (sequestosome 1, A170, OSIL, PDB3, ZIP3, p60, p62, p62B) (APC). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SQSTM1. It may not necessarily be applicable to this product.

NCBI GI #

13111937

NCBI GeneID

8878

NCBI Accession #

AAH03139.1

UniProt Related Accession #

Q13501

NCBI Official Full Name

Sequestosome 1

NCBI Official Synonym Full Names

sequestosome 1

NCBI Official Symbol

SQSTM1

NCBI Official Synonym Symbols

p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3

Protein Family

Sequestosome

NCBI Protein Information

sequestosome-1

Research Articles on SQSTM1

1. Polymerization, driven by a double arginine finger in the PB1 domain, is a general requirement for lysosomal targeting of p62.The filamentous assembly state of p62 is required for autophagosomal processing of the p62-specific cargo KEAP1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.