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ISLR2 Antibody – Sheep Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS616898

ISLR2 (Ig-superfamily containing LRR protein 2; also SST273) is a 100-110kD member of the LRR family of proteins. It is expressed on developing motor, sensory and interneurons. Mouse ISLR2 is 745 amino acids (aa) in length. It is a type I transmembrane… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ISLR2, Polyclonal Antibody
Full Product Name
ISLR2 (Immunoglobulin Superfamily Containing Leucine-Rich Repeat 2, SST273)
Product Gene Name
Product Synonym Names
Anti -ISLR2 (Immunoglobulin Superfamily Containing Leucine-Rich Repeat 2, SST273)
Clonality
Polyclonal
Isotype
IgG
Host
Sheep
Species Reactivity
Mouse
Form/Format
Supplied as a lyophilized powder from PBS with 5% trehalose. Reconstitute with 200ul 40-50% glycerol, PBS.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes mouse ISLR-2.
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
78,990 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (74421715..74429143). Location: 15q24.1
3D Structure
ModBase 3D Structure for Q6UXK2
Immunogen
NS0-derived, recombinant mouse ISLR-2.

Product Categories/Family for anti-ISLR2 antibody

Applications Tested/Suitable for anti-ISLR2 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-ISLR2 antibody
Suitable for use in Direct ELISA and Western Blot.
Dilution: Direct ELISA: 0.5-1ug/mL detection limit for rmISLR-2 ~ 0.8ng/well.
Western Blot: 0.1-0.2ug/mL detection limit for rmISLR-2 ~ 5ng/lane under non-reducing and reducing conditions.

Other Notes

Small volumes of anti-ISLR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ISLR2 purchase

MBS616898 is an antibody targeting ISLR2. Also known as ISLR2 (Immunoglobulin Superfamily Containing Leucine-Rich Repeat 2, SST273). Reactive in Mouse. Host: Sheep.

Additional Details

NCBI/Uniprot data below describe general gene information for ISLR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
immunoglobulin superfamily containing leucine-rich repeat protein 2
NCBI Official Synonym Full Names
immunoglobulin superfamily containing leucine-rich repeat 2
NCBI Official Symbol
ISLR2
NCBI Official Synonym Symbols
KIAA1465
UniProt Protein Name
Immunoglobulin superfamily containing leucine-rich repeat protein 2
UniProt Synonym Protein Names
Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein
UniProt Gene Name
ISLR2
UniProt Synonym Gene Names
KIAA1465; LINX
UniProt Entry Name
ISLR2_HUMAN
NCBI Protein Information
immunoglobulin superfamily containing leucine-rich repeat protein 2; OTTHUMP00000174969; leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein

UniProt Comments for ISLR2

ISLR2: Required for axon extension during neural development.

Protein type: Membrane protein, integral; Cell development/differentiation; Cell surface; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 15q24.1

Cellular Component: cell surface; plasma membrane; integral to membrane

Biological Process: positive regulation of axon extension
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-ISLR2 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with ISLR2 and Nerve
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