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FVT1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6169269

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FVT1, Monoclonal Antibody
Full Product Name
FVT1 (3-ketodihydrosphingosine Reductase, DHSR, FLJ36555, FLJ92680, FVT1, SDR35C1) (APC)
Product Gene Name
anti-FVT1 antibody
Product Synonym Names
3-ketodihydrosphingosine Reductase; DHSR; FLJ36555; FLJ92680; FVT1; SDR35C1
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
300000000
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified
Specificity
Recognizes FVT1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
29.0 kDa (266aa) confirmed by MALDI-TOF
OMIM
136440
3D Structure
ModBase 3D Structure for Q06136
Immunogen
FVT1 (AAH08797.1, 1aa-332aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Conjugate
APC

Product Categories/Family for anti-FVT1 antibody

Antibodies; Enzymes; Reductase
Applications Tested/Suitable for anti-FVT1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-FVT1 antibody
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-FVT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FVT1 purchase

MBS6169269 is an antibody targeting FVT1. Also known as FVT1 (3-ketodihydrosphingosine Reductase, DHSR, FLJ36555, FLJ92680, FVT1, SDR35C1) (APC). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for FVT1. It may not necessarily be applicable to this product.

NCBI GI #
14250664
NCBI GeneID
2531
NCBI Accession #
AAH08797.1
UniProt Primary Accession #
Q06136
UniProt Secondary Accession #
B2R5Y1; B4DMX0
UniProt Related Accession #
Q06136
NCBI Official Full Name
KDSR protein
NCBI Official Synonym Full Names
3-ketodihydrosphingosine reductase
NCBI Official Symbol
KDSR
NCBI Official Synonym Symbols
DHSR; FVT1; SDR35C1
UniProt Protein Name
3-ketodihydrosphingosine reductase
UniProt Synonym Protein Names
3-dehydrosphinganine reductase; Follicular variant translocation protein 1; FVT-1
UniProt Gene Name
KDSR
UniProt Synonym Gene Names
FVT1; KDS reductase; FVT-1
UniProt Entry Name
KDSR_HUMAN
NCBI Protein Information
3-ketodihydrosphingosine reductase

UniProt Comments for FVT1

FVT1: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS). A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region. Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: Lipid Metabolism - sphingolipid; Oxidoreductase; Membrane protein, multi-pass; Oncoprotein; EC 1.1.1.102; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: extracellular space; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: 3-dehydrosphinganine reductase activity

Biological Process: sphingolipid metabolic process; sphingolipid biosynthetic process; 3-keto-sphinganine metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FVT1 antibody

 Reference Product  PubMed Publications
 CERS2 antibody  >1 publications with FVT1 and CERS2
 CERS4 antibody  >1 publications with FVT1 and CERS4
 CERS6 antibody  >1 publications with FVT1 and CERS6
 CERS5 antibody  >1 publications with FVT1 and CERS5

Pathways associated with anti-FVT1 antibody

 Products by Pathway  Pathway Diagram
 Ceramide Biosynthesis Pathway antibodies  Ceramide Biosynthesis Pathway Diagram
 Ceramide Biosynthesis Pathway antibodies  Ceramide Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid De Novo Biosynthesis Pathway antibodies  Sphingolipid De Novo Biosynthesis Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram

Diseases associated with anti-FVT1 antibody

 Disease Name  Pubmed Publications
 Poisoning Antibodies  >1 publications with FVT1 and Poisoning

Organs/Tissues associated with anti-FVT1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with FVT1 and Kidney
 Liver Antibodies  >1 publications with FVT1 and Liver
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