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GTF2IRD1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6169287

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GTF2IRD1, Monoclonal Antibody
Full Product Name
GTF2IRD1 (GTF2I Repeat Domain Containing 1, BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1) (APC)
Product Gene Name
anti-GTF2IRD1 antibody
Product Synonym Names
GTF2I Repeat Domain Containing 1; BEN; CREAM1; GTF3; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12; hMusTRD1alpha1
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2C7
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified
Specificity
Recognizes GTF2IRD1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Immunogen
GTF2IRD1 (AAH18136, 1aa-959aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVSTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQGTASSLGFSPPALPPERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISFVQWPMYMVDYAGLNVQLPGPLNY
Conjugate
APC

Product Categories/Family for anti-GTF2IRD1 antibody

Antibodies; Disease Markers
Applications Tested/Suitable for anti-GTF2IRD1 antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-GTF2IRD1 antibody
Applications are based on unconjugated antibody.

Testing Data of anti-GTF2IRD1 antibody

Detection limit for recombinant GST tagged GTF2IRD1 is 1 ng/ml as a capture antibody.
Mouse Anti-GTF2IRD1 Monoclonal Antibody – Cat# MBS6169287

Western Blot (WB) of anti-GTF2IRD1 antibody

Western Blot analysis of GTF2IRD1 expression in transfected 293T cell line by GTF2IRD1 monoclonal antibody (M08), clone 2C7.

Lane 1: GTF2IRD1 transfected lysate (Predicted MW: 106 KDa).
Lane 2: Non-transfected lysate.
Mouse Anti-GTF2IRD1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6169287

Immunofluorescence (IF) of anti-GTF2IRD1 antibody

Immunofluorescence of monoclonal antibody to GTF2IRD1 on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-GTF2IRD1 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6169287

Immunofluorescence (IF) of anti-GTF2IRD1 antibody

Immunofluorescence of monoclonal antibody to GTF2IRD1 on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-GTF2IRD1 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6169287

Other Notes

Small volumes of anti-GTF2IRD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTF2IRD1 purchase

MBS6169287 is an antibody targeting GTF2IRD1. Also known as GTF2IRD1 (GTF2I Repeat Domain Containing 1, BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1) (APC). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2IRD1. It may not necessarily be applicable to this product.

NCBI GI #
17390303
NCBI GeneID
9569
NCBI Accession #
AAH18136
UniProt Related Accession #
Q9UHL9
NCBI Official Full Name
GTF2I repeat domain containing 1
NCBI Official Synonym Full Names
GTF2I repeat domain containing 1
NCBI Official Symbol
GTF2IRD1
NCBI Official Synonym Symbols
BEN; WBS; GTF3; RBAP2; CREAM1; MUSTRD1; WBSCR11; WBSCR12; hMusTRD1alpha1
Protein Family
General transcription factor II-I repeat domain-containing protein
NCBI Protein Information
general transcription factor II-I repeat domain-containing protein 1

NCBI Summary for GTF2IRD1

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
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Research Articles on GTF2IRD1

1. Study showed that GTF2IRD1 was overexpressed due to copy number amplification at Ch.7q in colorectal cancer (CRC). The expression of GTF2IRD1 was positively associated with the malignant pathological phenotype. Furthermore, high expression of GTF2IRD1 was an independent poor prognostic factor in CRC. Mechanistically, GTF2IRD1 promoted cell cycle progression by downregulation of TGFbetaR2 in CRC.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GTF2IRD1 antibody

 Reference Product  PubMed Publications
 SMAD3 antibody  >1 publications with GTF2IRD1 and SMAD3
 PIAS2 antibody  >1 publications with GTF2IRD1 and PIAS2

Pathways associated with anti-GTF2IRD1 antibody

 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 CGMP-PKG Signaling Pathway antibodies  CGMP-PKG Signaling Pathway Diagram
 CGMP-PKG Signaling Pathway antibodies  CGMP-PKG Signaling Pathway Diagram

Diseases associated with anti-GTF2IRD1 antibody

 Disease Name  Pubmed Publications
 Williams Syndrome Antibodies  >48 publications with GTF2IRD1 and Williams Syndrome
 Heart Diseases Antibodies  >34 publications with GTF2IRD1 and Heart Diseases
 Nervous System Diseases Antibodies  >33 publications with GTF2IRD1 and Nervous System Diseases
 Craniofacial Abnormalities Antibodies  >12 publications with GTF2IRD1 and Craniofacial Abnormalities
 Mental Disorders Antibodies  >6 publications with GTF2IRD1 and Mental Disorders
 Abnormalities, Multiple Antibodies  >5 publications with GTF2IRD1 and Abnormalities, Multiple
 Neural Tube Defects Antibodies  >1 publications with GTF2IRD1 and Neural Tube Defects
 Heart Defects, Congenital Antibodies  >1 publications with GTF2IRD1 and Heart Defects, Congenital
 Hyperplasia Antibodies  >1 publications with GTF2IRD1 and Hyperplasia

Organs/Tissues associated with anti-GTF2IRD1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >42 publications with GTF2IRD1 and Muscle
 Brain Antibodies  >17 publications with GTF2IRD1 and Brain
 Embryonic Tissue Antibodies  >7 publications with GTF2IRD1 and Embryonic Tissue
 Vascular Antibodies  >3 publications with GTF2IRD1 and Vascular
 Connective Tissue Antibodies  >2 publications with GTF2IRD1 and Connective Tissue
 Eye Antibodies  >2 publications with GTF2IRD1 and Eye
 Mouth Antibodies  >1 publications with GTF2IRD1 and Mouth
 Testis Antibodies  >1 publications with GTF2IRD1 and Testis
 Liver Antibodies  >1 publications with GTF2IRD1 and Liver
 Bone Antibodies  >1 publications with GTF2IRD1 and Bone
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