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CILP Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6169393

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CILP, Monoclonal Antibody
Full Product Name
CILP (Cartilage Intermediate layer Protein, Nucleotide pyrophosphohydrolase, CILP-1, HsT18872) (APC)
Product Gene Name
Product Synonym Names
Cartilage Intermediate layer Protein; Nucleotide pyrophosphohydrolase; CILP-1; HsT18872
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2D10
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified
Specificity
Recognizes CILP.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
52kDa
OMIM
603489
3D Structure
ModBase 3D Structure for O75339
Immunogen
CILP (NP_003604, 129aa-226aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
NCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFML
Conjugate
APC
Applications Tested/Suitable for anti-CILP antibody
ELISA (EIA)
Application Notes for anti-CILP antibody
Applications are based on unconjugated antibody.

Testing Data of anti-CILP antibody

Detection limit for recombinant GST tagged CILP is 0.3 ng/ml as a capture antibody.
Mouse Anti-CILP Monoclonal Antibody – Cat# MBS6169393

Other Notes

Small volumes of anti-CILP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CILP purchase

MBS6169393 is an antibody targeting CILP. Also known as CILP (Cartilage Intermediate layer Protein, Nucleotide pyrophosphohydrolase, CILP-1, HsT18872) (APC). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CILP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
cartilage intermediate layer protein 1 preproprotein
NCBI Official Synonym Full Names
cartilage intermediate layer protein
NCBI Official Symbol
CILP
NCBI Official Synonym Symbols
CILP-1; HsT18872
UniProt Protein Name
Cartilage intermediate layer protein 1
UniProt Synonym Protein Names
Cartilage intermediate-layer protein
UniProt Gene Name
CILP
UniProt Entry Name
CILP1_HUMAN
NCBI Protein Information
cartilage intermediate layer protein 1

NCBI Summary for CILP

Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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