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SCN3A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6169439

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SCN3A, Monoclonal Antibody
Full Product Name
SCN3A (Sodium Channel, Voltage-gated, Type III, alpha Subunit, KIAA1356, NAC3, Nav1.3) (APC)
Product Gene Name
Product Synonym Names
Sodium Channel; Voltage-gated; Type III; alpha Subunit; KIAA1356; NAC3; Nav1.3
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2F8
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified
Specificity
Recognizes SCN3A.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
OMIM
182391
3D Structure
ModBase 3D Structure for Q9NY46
Immunogen
SCN3A (NP_008853, 1861aa-1960aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
LCESGEMDALRIQMEDRFMASNPSKVSYEPITTTLKRKQEEVSAAIIQRNFRCYLLKQRLKNISSNYNKEAIKGRIDLPIKQDMIIDKLNGNSTPEKTDG
Conjugate
APC

Product Categories/Family for anti-SCN3A antibody

Applications Tested/Suitable for anti-SCN3A antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-SCN3A antibody
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-SCN3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCN3A purchase

MBS6169439 is an antibody targeting SCN3A. Also known as SCN3A (Sodium Channel, Voltage-gated, Type III, alpha Subunit, KIAA1356, NAC3, Nav1.3) (APC). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for SCN3A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sodium channel protein type 3 subunit alpha isoform 1
NCBI Official Synonym Full Names
sodium voltage-gated channel alpha subunit 3
NCBI Official Symbol
SCN3A
NCBI Official Synonym Symbols
NAC3; EIEE62; FFEVF4; Nav1.3
UniProt Protein Name
Sodium channel protein type 3 subunit alpha
UniProt Synonym Protein Names
Sodium channel protein brain III subunit alpha; Sodium channel protein type III subunit alpha; Voltage-gated sodium channel subtype III; Voltage-gated sodium channel subunit alpha Nav1.3
UniProt Gene Name
SCN3A
UniProt Synonym Gene Names
KIAA1356; NAC3
UniProt Entry Name
SCN3A_HUMAN
NCBI Protein Information
sodium channel protein type 3 subunit alpha

UniProt Comments for SCN3A

SCN3A: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.3/SCN3A subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, sodium; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q24

Cellular Component: voltage-gated sodium channel complex; cytoplasm; plasma membrane

Molecular Function: voltage-gated sodium channel activity

Biological Process: sodium ion transport; generation of action potential
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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