• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

UBE2Z Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6169856

Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE2Z is an E2… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UBE2Z, Monoclonal Antibody
Full Product Name
UBE2Z (Ubiquitin-conjugating Enzyme E2Z, FLJ13855, HOYS7, USE1) (APC)
Product Gene Name
Product Synonym Names
Ubiquitin-conjugating Enzyme E2Z; FLJ13855; HOYS7; USE1
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4B1
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified
Specificity
Recognizes UBE2Z.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
27kDa
OMIM
611362
3D Structure
ModBase 3D Structure for Q9H832
Immunogen
UBE2Z (NP_075567, 136aa-225aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
IRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQGQTMQDPFGEKRGHFDYQSLLMRLGLIRQKVLERLHNENA
Conjugate
APC

Product Categories/Family for anti-UBE2Z antibody

Applications Tested/Suitable for anti-UBE2Z antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-UBE2Z antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-UBE2Z antibody

UBE2Z monoclonal antibody (M01), clone 4B1. Western Blot analysis of UBE2Z expression in K-562.
Mouse Anti-UBE2Z Monoclonal Antibody – Cat# MBS6169856

Testing Data of anti-UBE2Z antibody

Detection limit for recombinant GST tagged UBE2Z is 3 ng/ml as a capture antibody.
Mouse Anti-UBE2Z Monoclonal Antibody, Testing Data – Cat# MBS6169856

Immunofluorescence (IF) of anti-UBE2Z antibody

Immunofluorescence of monoclonal antibody to UBE2Z on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-UBE2Z Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6169856

Immunofluorescence (IF) of anti-UBE2Z antibody

Immunofluorescence of monoclonal antibody to UBE2Z on HeLa cell. [antibody concentration 10 ug/ml]
Mouse Anti-UBE2Z Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6169856

Other Notes

Small volumes of anti-UBE2Z antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UBE2Z purchase

MBS6169856 is an antibody targeting UBE2Z. Also known as UBE2Z (Ubiquitin-conjugating Enzyme E2Z, FLJ13855, HOYS7, USE1) (APC). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for UBE2Z. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ubiquitin-conjugating enzyme E2 Z
NCBI Official Synonym Full Names
ubiquitin conjugating enzyme E2 Z
NCBI Official Symbol
UBE2Z
NCBI Official Synonym Symbols
USE1; HOYS7
UniProt Protein Name
Ubiquitin-conjugating enzyme E2 Z
UniProt Synonym Protein Names
Uba6-specific E2 conjugating enzyme 1; Use1; Ubiquitin carrier protein Z; Ubiquitin-protein ligase Z
UniProt Gene Name
UBE2Z
UniProt Synonym Gene Names
Use1
UniProt Entry Name
UBE2Z_HUMAN
NCBI Protein Information
ubiquitin-conjugating enzyme E2 Z

NCBI Summary for UBE2Z

This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012]

UniProt Comments for UBE2Z

Function: Catalyzes the covalent attachment of ubiquitin to other proteins

By similarity. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation. Ref.1 Ref.10

Catalytic activity: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway: Protein modification; protein ubiquitination.

Subcellular location: Cytoplasm. Nucleus Ref.9.

Tissue specificity: Widely expressed. Highly in placenta, pancreas, spleen and testis. Ref.1 Ref.9

Sequence similarities: Belongs to the ubiquitin-conjugating enzyme family.

Sequence caution: The sequence AAH15890.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB14724.1 differs from that shown. Reason: Erroneous initiation.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000