Chicken Anti-UQCRC2 Polyclonal Antibody – Cat# MBS617525

Western Blot: E coli-derived fusion protein as test antigen. Affi-pure IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2) Antibody – Chicken Polyclonal

Name: UQCRC2 Antibody; Polyclonal; Chicken; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS617525
Price: 890 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS617525

UQCRC2 is a component of the ubiquinol-cytochrome c reductase complex (complex III), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. More details

$890 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2), Polyclonal Antibody

Full Product Name

Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2)

Product Gene Name

anti-UQCRC2 antibody

Product Synonym Names

Anti -Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2)

Clonality

Polyclonal

Isotype

IgY

Host

Chicken

Species Reactivity

Human, Mouse, Rat

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human UQCRC2. Species Crossreactivity: Mouse and rat.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

48,443 Da

Chromosome Location

Chromosome: 16; NC_000016.9 (21964609..21994668). Location: 16p12

OMIM

191329

3D Structure

ModBase 3D Structure for P22695

Immunogen

Synthetic peptide corresponding to aa231-453

Product Categories/Family for anti-UQCRC2 antibody

Antibodies; Abs to Enzymes; Cytochrome

Applications Tested/Suitable for anti-UQCRC2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-UQCRC2 antibody

Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:1000-1:2000

Other Notes

Small volumes of anti-UQCRC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UQCRC2 purchase

MBS617525 is an antibody targeting UQCRC2. Also known as Ubiquinol Cytochrome C Reductase Core Protein II (UQCRC2). Reactive in Human, Mouse, Rat. Host: Chicken.

Additional Details

NCBI/Uniprot data below describe general gene information for UQCRC2. It may not necessarily be applicable to this product.

NCBI GI #

13111931

NCBI GeneID

7385

UniProt Primary Accession #

P22695

UniProt Secondary Accession #

Q9BQ05; B3KSN4

UniProt Related Accession #

P22695

NCBI Official Full Name

Ubiquinol-cytochrome c reductase core protein II

NCBI Official Synonym Full Names

ubiquinol-cytochrome c reductase core protein II

NCBI Official Symbol

UQCRC2

NCBI Official Synonym Symbols

QCR2; UQCR2

UniProt Protein Name

Cytochrome b-c1 complex subunit 2, mitochondrial

UniProt Synonym Protein Names

Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2

UniProt Gene Name

UQCRC2

UniProt Entry Name

QCR2_HUMAN

NCBI Protein Information

cytochrome b-c1 complex subunit 2, mitochondrial; core protein II; OTTHUMP00000162338; complex III subunit 2; ubiquinol-cytochrome-c reductase complex core protein 2

NCBI Summary for UQCRC2

The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015]

UniProt Comments for UQCRC2

UQCRC2: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.

Protein type: EC 1.10.2.2; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 16p12

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III

Molecular Function: protein binding; metal ion binding; metalloendopeptidase activity; protein complex binding

Biological Process: cellular metabolic process; aerobic respiration; proteolysis; oxidative phosphorylation

Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 5

Research Articles on UQCRC2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UQCRC2 antibody

Reference Product	PubMed Publications
UQCRC1 antibody	>3 publications with UQCRC2 and UQCRC1

Pathways associated with anti-UQCRC2 antibody

Products by Pathway	Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Cardiac Muscle Contraction Pathway antibodies	Cardiac Muscle Contraction Pathway Diagram
Cardiac Muscle Contraction Pathway antibodies	Cardiac Muscle Contraction Pathway Diagram
Electron Transport Chain Pathway antibodies	Electron Transport Chain Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram

Diseases associated with anti-UQCRC2 antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with UQCRC2 and Breast Neoplasms
Inflammation Antibodies	>1 publications with UQCRC2 and Inflammation
Carcinoma Antibodies	>1 publications with UQCRC2 and Carcinoma
Neurodegenerative Diseases Antibodies	>1 publications with UQCRC2 and Neurodegenerative Diseases
Infertility, Male Antibodies	>1 publications with UQCRC2 and Infertility, Male
Genetic Diseases, Inborn Antibodies	>1 publications with UQCRC2 and Genetic Diseases, Inborn

Organs/Tissues associated with anti-UQCRC2 antibody

Organ/Tissue Name	Pubmed Publications
Epididymis Antibodies	>1 publications with UQCRC2 and Epididymis
Spinal Cord Antibodies	>1 publications with UQCRC2 and Spinal Cord
Nerve Antibodies	>1 publications with UQCRC2 and Nerve
Muscle Antibodies	>1 publications with UQCRC2 and Muscle
Lung Antibodies	>1 publications with UQCRC2 and Lung
Heart Antibodies	>1 publications with UQCRC2 and Heart
Brain Antibodies	>1 publications with UQCRC2 and Brain