Goat Anti-CDHR5 Polyclonal Antibody – Cat# MBS617598

MUCDHL (CDHR5) Antibody – Goat Polyclonal

Name: CDHR5 Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS617598
Price: 1090 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS617598

Mucin and cadherin-like protein (MUCDHL), also known as -protocadherin, is a 110kD type I transmembrane protein that is both O- and N-glycosylated. It is a calcium-dependent cell adhesion protein in the cadherin superfamily. MUCDHL is found on intestinal and… More details

$1090 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MUCDHL (CDHR5), Polyclonal Antibody

Full Product Name

MUCDHL (Mucin and Cadherin-Like Protein, mu-Protocadherin)

Product Gene Name

anti-CDHR5 antibody

Product Synonym Names

Anti -MUCDHL (Mucin and Cadherin-Like Protein, mu-Protocadherin)

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Human

Form/Format

Supplied as a lyophilized powder from a 0.2um filtered solution in PBS with 5% trehalose. Reconstitute with sterile PBS, 40-50% glycerol. If 0.5ml is used, the concentration will be 0.2mg/ml.

Purity/Purification

Affinity Purified
Purified by human MUCDHL affinity chromatography.

Specificity

Selected for its ability to recognize human MUCDHL in direct ELISAs and Western Blots. In these formats, this antibody shows ~10% crossreactivity with rmMUCDHL.

Preparation and Storage

Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile PBS with 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

69,610 Da

Chromosome Location

chromosome: 11; Location: 11p15.5

3D Structure

ModBase 3D Structure for Q58EZ6

Immunogen

E. coli-derived rhMUCDHL (aa26-434)

Product Categories/Family for anti-CDHR5 antibody

Antibodies; Abs to Cadherin

Applications Tested/Suitable for anti-CDHR5 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-CDHR5 antibody

Western Blot: This antibody can be used at 0.1-0.2ug/ml with the appropriate secondary reagents to detect human MUCDHL. The detection limit for rhMUCDHL is approximately 5 ng/lane under non-reducing and reducing conditions., Direct ELISA: This antibody can be used at 0.5-1.0ug/ml with the appropriate secondary reagents to detect human MUCDHL. The detection limit for rhMUCDHL is approximately 0.3 ng/well., Optimal dilutions should be determined by each laboratory for each application.

Other Notes

Small volumes of anti-CDHR5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDHR5 purchase

MBS617598 is an antibody targeting CDHR5. Also known as MUCDHL (Mucin and Cadherin-Like Protein, mu-Protocadherin). Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for CDHR5. It may not necessarily be applicable to this product.

NCBI GI #

37181861

NCBI GeneID

53841

UniProt Primary Accession #

Q58EZ6

UniProt Related Accession #

Q58EZ6; Q9HBB8

NCBI Official Full Name

MUCDHL

NCBI Official Synonym Full Names

cadherin-related family member 5

NCBI Official Symbol

CDHR5

NCBI Official Synonym Symbols

MUCDHL; MUPCDH; MU-PCDH; FLJ20219; CDHR5

UniProt Protein Name

Mucin-like protocadherin

Protein Family

Cadherin-related family

UniProt Gene Name

MUPCDH

UniProt Entry Name

Q58EZ6_HUMAN

NCBI Protein Information

cadherin-related family member 5; mu-protocadherin; OTTHUMP00000162884; mucin and cadherin-like protein

NCBI Summary for CDHR5

This gene is a novel mucin-like gene that is a member of the cadherin superfamily. While encoding nonpolymorphic tandem repeats rich in proline, serine and threonine similar to mucin proteins, the gene also contains sequence encoding calcium-binding motifs found in all cadherins. The role of the hybrid extracellular region and the specific function of this protein have not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

UniProt Comments for CDHR5

MUCDHL: Acts as a calcium-dependent cell adhesion protein. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: plasma membrane; integral to membrane

Molecular Function: protein binding; beta-catenin binding; calcium ion binding

Biological Process: cell adhesion; homophilic cell adhesion

Research Articles on CDHR5

1. MUCDHL genes are biallelically expressed in multiple fetal and adult tissues both in humans and in mice
2. identifed the human mu-protocadherin ortholog and examined its expression in the developing kidney

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CDHR5 antibody

Disease Name	Pubmed Publications
Cell Transformation, Neoplastic Antibodies	>1 publications with CDHR5 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-CDHR5 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>2 publications with CDHR5 and Kidney
Liver Antibodies	>1 publications with CDHR5 and Liver
Intestine Antibodies	>1 publications with CDHR5 and Intestine