Rabbit Anti-GIP Polyclonal Antibody – Cat# MBS617780

Gastric Inhibitory Peptide (GIP) Antibody – Rabbit Polyclonal

Name: GIP Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS617780
Price: 965 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS617780

Glucagon is a member of a multigene family comprising of Secretin, Vasoactive Intestinal Peptide (VIP), Gastric Inhibitory Peptide (GIP) and others like Glicentin and Oxyntomodulin (OXM), which differs from glucagon by C-terminal octapeptide. The glucagon… More details

$965 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Gastric Inhibitory Peptide (GIP), Polyclonal Antibody

Full Product Name

Gastric Inhibitory Peptide (GIP)

Product Gene Name

anti-GIP antibody

Product Synonym Names

Anti -Gastric Inhibitory Peptide (GIP)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a lyophilized powder. Reconstitute with 100ul sterile PBS.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human Gastric Inhibitory Peptide.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

17,108 Da

Chromosome Location

Chromosome: 17; NC_000017.10 (47035918..47045955, complement). Location: 17q21.3-q22

OMIM

137240

3D Structure

ModBase 3D Structure for P09681

Immunogen

Synthetic peptide corresponding to 10aa at the middle region, cytoplasmic domain of human GIP. Species Sequence Homology: mouse, porcine and rat - 90%.

Product Categories/Family for anti-GIP antibody

Antibodies; Abs to Serum Proteins

Applications Tested/Suitable for anti-GIP antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-GIP antibody

Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1-10ug/ml using Chemiluminescence technique.
ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml.

Other Notes

Small volumes of anti-GIP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GIP purchase

MBS617780 is an antibody targeting GIP. Also known as Gastric Inhibitory Peptide (GIP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GIP. It may not necessarily be applicable to this product.

NCBI GI #

4758436

NCBI GeneID

2695

NCBI Accession #

NP_004114.1

UniProt Primary Accession #

P09681

UniProt Secondary Accession #

Q4VB42; Q6NTD3

UniProt Related Accession #

P09681

GenBank Nucleotide #

NM_004123.2

NCBI Official Full Name

gastric inhibitory polypeptide preproprotein

NCBI Official Synonym Full Names

gastric inhibitory polypeptide

NCBI Official Symbol

GIP

UniProt Protein Name

Gastric inhibitory polypeptide

UniProt Synonym Protein Names

Glucose-dependent insulinotropic polypeptide; Incretin hormone

Protein Family

Copia protein

UniProt Gene Name

GIP

UniProt Synonym Gene Names

GIP

UniProt Entry Name

GIP_HUMAN

NCBI Protein Information

gastric inhibitory polypeptide; incretin hormone; glucose-dependent insulinotropic polypeptide

NCBI Summary for GIP

This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]

UniProt Comments for GIP

GIP: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. Belongs to the glucagon family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17q21.3-q22

Cellular Component: extracellular space; cell soma; endoplasmic reticulum lumen; extracellular region

Molecular Function: hormone activity

Biological Process: response to drug; response to peptide hormone stimulus; adult locomotory behavior; positive regulation of insulin secretion; female pregnancy; response to lipid; signal transduction; sensory perception of pain; response to amino acid stimulus; response to organic cyclic substance; endocrine pancreas development; memory; response to starvation; response to selenium ion; cellular protein metabolic process; response to glucose stimulus; response to axon injury; regulation of insulin secretion

Research Articles on GIP

1. Data suggest that postprandial plasma levels of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP1) are increased after consumption of buckwheat crackers versus rice crackers in healthy and type 2 diabetic subjects.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-GIP antibody

Reference Product	PubMed Publications
GIPR antibody	>82 publications with GIP and GIPR
DPP4 antibody	>48 publications with GIP and DPP4
BAX antibody	>5 publications with GIP and BAX
GATA4 antibody	>3 publications with GIP and GATA4
RETN antibody	>1 publications with GIP and RETN

Pathways associated with anti-GIP antibody

Products by Pathway	Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Glucagon-type Ligand Receptors Pathway antibodies	Glucagon-type Ligand Receptors Pathway Diagram
Incretin Synthesis, Secretion, And Inactivation Pathway antibodies	Incretin Synthesis, Secretion, And Inactivation Pathway Diagram
Insulin Secretion Pathway antibodies	Insulin Secretion Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Peptide Hormone Metabolism Pathway antibodies	Peptide Hormone Metabolism Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with anti-GIP antibody

Disease Name	Pubmed Publications
Diabetes Mellitus, Type 2 Antibodies	>403 publications with GIP and Diabetes Mellitus, Type 2
Neoplasms Antibodies	>162 publications with GIP and Neoplasms
Weight Loss Antibodies	>93 publications with GIP and Weight Loss
Diabetes Complications Antibodies	>77 publications with GIP and Diabetes Complications
Weight Gain Antibodies	>56 publications with GIP and Weight Gain
Neurologic Manifestations Antibodies	>42 publications with GIP and Neurologic Manifestations
Carcinoma Antibodies	>41 publications with GIP and Carcinoma
Hyperplasia Antibodies	>40 publications with GIP and Hyperplasia
Kidney Diseases Antibodies	>29 publications with GIP and Kidney Diseases
Hypertension Antibodies	>23 publications with GIP and Hypertension

Organs/Tissues associated with anti-GIP antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>446 publications with GIP and Intestine
Stomach Antibodies	>152 publications with GIP and Stomach