Rabbit Anti-EPHA6 Polyclonal Antibody – Cat# MBS617885

EPHA6 Antibody – Rabbit Polyclonal

Name: EPHA6 Antibody; Polyclonal; Rabbit; Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS617885
Price: 575 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS617885

EPA6 is a member of the EPH sub-family of receptor protein tyrosine kinases (PTKs). It is the first EPH-related receptor tyrosine kinase to be reported as found in both fetal and adult inner ear tissue. More details

$575 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EPA6 (EPHA6), Polyclonal Antibody

Full Product Name

EPA6 (EHK2)

Product Gene Name

anti-EPHA6 antibody

Product Synonym Names

Anti -EPA6 (EHK2)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Mouse, Rat

Form/Format

Supplied as a liquid in glycerol, 0.05% sodium azide.

Purity/Purification

Purified
Purified

Specificity

This sequence is 100% homologous in rat and 68% homologous to human EPB4.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Chromosome Location

Chromosome: 3; NC_000003.11 (96533425..97467786). Location: 3q11.2

3D Structure

ModBase 3D Structure for Q6UWM0

Immunogen

Synthetic peptide corresponding to amino acids 665-680 (cytoplasmic region) of mouse EPA6.

Product Categories/Family for anti-EPHA6 antibody

Antibodies; Abs to Protein Kinases

Applications Tested/Suitable for anti-EPHA6 antibody

ELISA (EL/EIA)

Application Notes for anti-EPHA6 antibody

Suitable for use in ELISA.
Dilution: ELISA: 1:100-1:1000

Other Notes

Small volumes of anti-EPHA6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPHA6 purchase

MBS617885 is an antibody targeting EPHA6. Also known as EPA6 (EHK2). Reactive in Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EPHA6. It may not necessarily be applicable to this product.

NCBI GI #

145312251

NCBI GeneID

285220

NCBI Accession #

NP_001073917.2

UniProt Primary Accession #

Q6UWM0

UniProt Related Accession #

Q6UWM0; Q9UF33

GenBank Nucleotide #

NM_001080448.2

NCBI Official Full Name

ephrin type-A receptor 6 isoform a

NCBI Official Synonym Full Names

EPH receptor A6

NCBI Official Symbol

EPHA6

NCBI Official Synonym Symbols

EPA6; FLJ35246; PRO57066; DKFZp434C1418

UniProt Protein Name

EPA6

Protein Family

Ephrin type-A receptor

UniProt Entry Name

Q6UWM0_HUMAN

NCBI Protein Information

ephrin type-A receptor 6; EHK-2; OTTHUMP00000214353; OTTHUMP00000217916; OTTHUMP00000217917; EPH homology kinase 2; ephrin receptor EphA6

UniProt Comments for EPHA6

EphA6: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; EC 2.7.10.1; Kinase, protein; Protein kinase, tyrosine (receptor); Protein kinase, TK; TK group; Eph family

Chromosomal Location of Human Ortholog: 3q11.2

Cellular Component: nucleoplasm; integral to plasma membrane; plasma membrane

Molecular Function: ephrin receptor activity; ATP binding

Biological Process: axon guidance; peptidyl-tyrosine phosphorylation; ephrin receptor signaling pathway

Research Articles on EPHA6

1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EPHA6 antibody

Reference Product	PubMed Publications
EFNA1 antibody	>1 publications with EPHA6 and EFNA1

Pathways associated with anti-EPHA6 antibody

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
EPHA Forward Signaling Pathway antibodies	EPHA Forward Signaling Pathway Diagram
EphrinA-EPHA Pathway antibodies	EphrinA-EPHA Pathway Diagram

Diseases associated with anti-EPHA6 antibody

Disease Name	Pubmed Publications
Mental Disorders Antibodies	>2 publications with EPHA6 and Mental Disorders
Neoplasms Antibodies	>1 publications with EPHA6 and Neoplasms
Memory Disorders Antibodies	>1 publications with EPHA6 and Memory Disorders
Movement Disorders Antibodies	>1 publications with EPHA6 and Movement Disorders
Cardiovascular Diseases Antibodies	>1 publications with EPHA6 and Cardiovascular Diseases
Death Antibodies	>1 publications with EPHA6 and Death
Necrosis Antibodies	>1 publications with EPHA6 and Necrosis
Inflammation Antibodies	>1 publications with EPHA6 and Inflammation
Schizophrenia Antibodies	>1 publications with EPHA6 and Schizophrenia
Learning Disorders Antibodies	>1 publications with EPHA6 and Learning Disorders

Organs/Tissues associated with anti-EPHA6 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>12 publications with EPHA6 and Brain
Kidney Antibodies	>1 publications with EPHA6 and Kidney
Prostate Antibodies	>1 publications with EPHA6 and Prostate
Testis Antibodies	>1 publications with EPHA6 and Testis