Rabbit Anti-foxi4.2-a Polyclonal Antibody – Cat# MBS617999

foxi4.2-a Antibody – Rabbit Polyclonal

Name: foxi4.2-a Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS617999
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS617999

MBS617999 is an antibody targeting foxi4.2-a. Also known as FOXI1a (Forkhead Box I1a, FKHL10, Forkhead-Related Transcription Factor 6, FREAC6, HNF-3 Forkhead Homolog 3, HFH3). Reactive in Human. Host: Rabbit. More details

$305 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FOXI1a (foxi4.2-a), Polyclonal Antibody

Full Product Name

FOXI1a (Forkhead Box I1a, FKHL10, Forkhead-Related Transcription Factor 6, FREAC6, HNF-3 Forkhead Homolog 3, HFH3)

Product Gene Name

anti-foxi4.2-a antibody

Product Synonym Names

Anti -FOXI1a (Forkhead Box I1a, FKHL10, Forkhead-Related Transcription Factor 6, FREAC6, HNF-3 Forkhead Homolog 3, HFH3)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, sodium azide, before the addition of glycerol to 40%.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human FOXI1a.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

41,388 Da

3D Structure

ModBase 3D Structure for Q91904

Immunogen

Synthetic peptide (KRKSDVSSSTASLAL-C) CORRESPONDING TO HUMAN FOXH1A (KLH). Molecular Weight: 41.3KD.

Product Categories/Family for anti-foxi4.2-a antibody

Antibodies; Abs to Transcription Factors

Applications Tested/Suitable for anti-foxi4.2-a antibody

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-foxi4.2-a antibody

Suitable for use in ELISA, Immunohistochemistry and Western Blot.
Dilution: ELISA Titer:1:250,000.
Western Blot: 1ug/ml. Band detected at 40kD using 293 cell lines and at 65kD using human colon.
Immunohistochemistry: 10ug/ml

Other Notes

Small volumes of anti-foxi4.2-a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for foxi4.2-a. It may not necessarily be applicable to this product.

NCBI GI #

147906729

NCBI GeneID

397954

NCBI Accession #

NP_001081617.1

UniProt Primary Accession #

Q91904

UniProt Secondary Accession #

Q68F03

UniProt Related Accession #

Q91904

GenBank Nucleotide #

NM_001088148.1

NCBI Official Full Name

forkhead box protein I1-A

NCBI Official Synonym Full Names

forkhead box I4, gene 2

NCBI Official Symbol

foxi4.2-a

NCBI Official Synonym Symbols

xfd2; XFD2'; foxi1a; foxi4.2; MGC83274

UniProt Protein Name

Forkhead box protein I1-A

UniProt Synonym Protein Names

Fork head domain-related protein 2

Protein Family

Forkhead box protein

UniProt Gene Name

foxi1-a

UniProt Entry Name

FXI1A_XENLA

NCBI Protein Information

forkhead box protein I1-A; xFD-2; foxI1-A; xFoxI1a; fork head domain-related protein 2

UniProt Comments for foxi4.2-a

Function: Transcription factor. Essential for ventral specification of the early cephalic (head) ectoderm during gastrulation, playing a role in the non-neural versus neural cell fate choice. Binds to DNA via the target sequence 5'-[AG]TAAA[CT]A-3', with 5'-ATAAACA-3' being the preferred binding site. Ref.4 Ref.6

Subcellular location: Nucleus Ref.5.

Tissue specificity: Initially localized to the animal hemisphere (the presumptive ectoderm) of early-mid blastula embryos. Becomes restricted to head placodes, excluding the otic placodes, by the tailbud stages. Ref.1 Ref.5 Ref.6

Developmental stage: Expression begins at the early-mid blastula stage. Levels are highest during the blastula and gastrula stages, after which levels decreases until somite segregation. At later developmental stages, expressed at a slightly lower level than foxi1-B. Ref.1 Ref.5 Ref.6

Induction: Induced by Bmp-signaling. Suppressed by Wnt-signaling. Ref.5 Ref.6

Sequence similarities: Contains 1 fork-head DNA-binding domain.

Sequence caution: The sequence AAH80044.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on foxi4.2-a

1. Foxi1a is an essential regulator of ventral specification of the early head ectoderm during gastrulation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.