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DLD Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6180439

This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DLD, Monoclonal Antibody
Full Product Name
DLD (Dihydrolipoamide Dehydrogenase, DLDH, E3, GCSL, LAD, PHE3) (HRP)
Product Gene Name
Product Synonym Names
Dihydrolipoamide Dehydrogenase; DLDH; E3; GCSL; LAD; PHE3
Clonality
Monoclonal
Isotype
IgG3,k
Clone Number
2D4
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Purity/Purification
Purified
Specificity
Recognizes DLD.
Preparation and Storage
May be stored at 4 degree C. For long-term storage, aliquot and store at 4 degree C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
DLD (AAH18696, 1aa-509aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF
Conjugate
HRP

Product Categories/Family for anti-DLD antibody

Applications Tested/Suitable for anti-DLD antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-DLD antibody
Applications are based on unconjugated antibody.

Testing Data of anti-DLD antibody

Immunoperoxidase of monoclonal antibody to DLD on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
Mouse Anti-DLD Monoclonal Antibody – Cat# MBS6180439

Immunohistochemistry (IHC) of anti-DLD antibody

Immunoperoxidase of monoclonal antibody to DLD on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml]
Mouse Anti-DLD Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6180439

Testing Data of anti-DLD antibody

Detection limit for recombinant GST tagged DLD is approximately 1ng/ml as a capture antibody.
Mouse Anti-DLD Monoclonal Antibody, Testing Data – Cat# MBS6180439

Other Notes

Small volumes of anti-DLD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLD purchase

MBS6180439 is an antibody targeting DLD. Also known as DLD (Dihydrolipoamide Dehydrogenase, DLDH, E3, GCSL, LAD, PHE3) (HRP). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DLD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Related Accession #
NCBI Official Full Name
Dihydrolipoamide dehydrogenase
NCBI Official Synonym Full Names
dihydrolipoamide dehydrogenase
NCBI Official Symbol
DLD
NCBI Official Synonym Symbols
E3; LAD; DLDD; DLDH; GCSL; PHE3
NCBI Protein Information
dihydrolipoyl dehydrogenase, mitochondrial

NCBI Summary for DLD

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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