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Perilipin (PLIN1) Antibody – Guinea Pig Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS618136

Perilipins build a family of phosphoproteins. The predominant forms in adipocytes, perilipin A and B arise by alternative RNA splicing from a single gene, generating polypepides of 57 and 46kD, respectively. The N-terminus, however, remains unchanged. The… More details

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Product Overview

Online Datasheet in PDF
Product Name
Perilipin (PLIN1), Polyclonal Antibody
Full Product Name
Perilipin
Product Gene Name
Product Synonym Names
Anti -Perilipin
Clonality
Polyclonal
Isotype
IgG
Host
Guinea pig
Species Reactivity
Human, Mouse, Rat
Form/Format
Supplied as a liquid, 0.09% sodium azide.
Purity/Purification
Serum
Serum
Specificity
Recognizes perilipins (A and B) at ~57 and ~46kD, respectively. Does not cross-react with ADRP (adipophilin) or TIP47 proteins. Species Crossreactivity: human, rat and mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Molecular Weight
55,990 Da
Chromosome Location
Chromosome: 15; NC_000015.9 (90207598..90222648, complement). Location: 15q26
OMIM
170290
3D Structure
ModBase 3D Structure for O60240
Immunogen
Duplicated N-terminus of perilipin
Applications Tested/Suitable for anti-PLIN1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PLIN1 antibody
Suitable for use in Western Blot and Immunohistochemistry
Dilution: Western Blot (ECL): 1:2000
Immunohistochemistry: 1:100-1:200 for 1 hour at RT on paraffin sections after microwave treatment or on frozen sections.

Other Notes

Small volumes of anti-PLIN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLIN1 purchase

MBS618136 is an antibody targeting PLIN1. Also known as Perilipin. Reactive in Human, Mouse, Rat. Host: Guinea pig.

Additional Details

NCBI/Uniprot data below describe general gene information for PLIN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
perilipin
NCBI Official Synonym Full Names
perilipin 1
NCBI Official Symbol
PLIN1
NCBI Official Synonym Symbols
PERI; PLIN; FPLD4
UniProt Protein Name
Perilipin-1
UniProt Synonym Protein Names
Lipid droplet-associated protein
Protein Family
UniProt Gene Name
PLIN1
UniProt Synonym Gene Names
PERI; PLIN
UniProt Entry Name
PLIN1_HUMAN
NCBI Protein Information
perilipin-1; OTTHUMP00000194689; OTTHUMP00000228582; lipid droplet-associated protein

NCBI Summary for PLIN1

The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq]
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UniProt Comments for PLIN1

perilipin 1: an adipocyte protein of the peripilin family. A modulator of adipocyte lipid metabolism, coating lipid storage droplets to protect them from being broken down by hormone-sensitive lipase. A major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 15q26

Cellular Component: endoplasmic reticulum; lipid particle; cytosol

Molecular Function: lipid binding

Biological Process: triacylglycerol catabolic process; lipid metabolic process

Disease: Lipodystrophy, Familial Partial, Type 4
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PLIN1 antibody

 Reference Product  PubMed Publications
 ABHD5 antibody  >2 publications with PLIN1 and ABHD5
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