Goat Anti-RARRES1 Polyclonal Antibody – Cat# MBS618172

Western Blot of mouse spleen tissue lysates using MBS618172 (1ug/ml) followed by IgG (HRP) Anti-Goat. A specific band was detected for RARRES1 at approximately 33kD (as indicated). This experiment was conducted under reducing conditions.

Retinoic Acid Receptor Responder 1 (RARRES1) Antibody – Goat Polyclonal

Name: RARRES1 Antibody; Polyclonal; Goat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS618172
Price: 1030 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS618172

RARRES1 (Retinoic Acid Receptor Responder 1; also Tig1) is a member of the protease inhibitor I47 family of proteins. It is expressed in epithelium, including keratinocytes, plus prostate and breast epithelium. It is considered to be a tumor-suppressor… More details

$1030 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Retinoic Acid Receptor Responder 1 (RARRES1), Polyclonal Antibody

Full Product Name

Retinoic Acid Receptor Responder 1 (RARRES1, Tig1)

Product Gene Name

anti-RARRES1 antibody

Product Synonym Names

Anti -Retinoic Acid Receptor Responder 1 (RARRES1, Tig1)

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Mouse

Form/Format

Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes mouse RARRES1. Does not recognize recombinant human RARRES1.

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

33,285 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (158414897..158450275, complement). Location: 3q25.32

OMIM

605090

3D Structure

ModBase 3D Structure for P49788

Immunogen

E. coli-derived recombinant mouse RARRES1 (aa108-349), Accession #XP_001475843. Species Sequence Homology: rat (88%), human (79%).

Product Categories/Family for anti-RARRES1 antibody

Antibodies; Abs to Protease Inhibitors

Applications Tested/Suitable for anti-RARRES1 antibody

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-RARRES1 antibody

Suitable for use in Direct ELISA, Western Blot and Immunohistochemistry.
Dilution: Direct ELISA: 0.5-1ug/ml; Detection limit is ~0.3ng/well.
Western Blot: 1ug/ml
Immunohistochemistry (Fluorescence): 10ug/ml; Detects RARRES1 in cryosections of mouse liver. Tissue was fixed overnight in 4% PFA + 14% picric acid in PBS at 4 degree C. Sections were blocked with 10% donkey serum and 0.1% Triton X-100 in PBS, 1% BSA for 45 minutes at RT. After blocking, sections were incubated with R1691-97 for 3 hours at RT, followed by donkey anti-goat IgG (NL557) for 1 hour at RT. Between each step, cells were washed with PBS, 0.1% BSA.

Other Notes

Small volumes of anti-RARRES1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RARRES1 purchase

MBS618172 is an antibody targeting RARRES1. Also known as Retinoic Acid Receptor Responder 1 (RARRES1, Tig1). Reactive in Mouse. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for RARRES1. It may not necessarily be applicable to this product.

NCBI GI #

46255043

NCBI GeneID

5918

NCBI Accession #

NP_996846.1

UniProt Primary Accession #

P49788

UniProt Secondary Accession #

Q8N1D7

UniProt Related Accession #

P49788

GenBank Nucleotide #

NM_206963.1

NCBI Official Full Name

retinoic acid receptor responder protein 1 isoform 1

NCBI Official Synonym Full Names

retinoic acid receptor responder (tazarotene induced) 1

NCBI Official Symbol

RARRES1

NCBI Official Synonym Symbols

TIG1

UniProt Protein Name

Retinoic acid receptor responder protein 1

UniProt Synonym Protein Names

RAR-responsive protein TIG1; Tazarotene-induced gene 1 protein

Protein Family

Retinoic acid receptor responder protein

UniProt Gene Name

RARRES1

UniProt Synonym Gene Names

TIG1

UniProt Entry Name

TIG1_HUMAN

NCBI Protein Information

retinoic acid receptor responder protein 1; OTTHUMP00000213561; OTTHUMP00000213562; OTTHUMP00000213563; RAR-responsive protein TIG1; tazarotene-induced gene 1 protein

NCBI Summary for RARRES1

This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq]

UniProt Comments for RARRES1

RARRES1: identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q25.32

Cellular Component: integral to membrane

Biological Process: negative regulation of cell proliferation

Research Articles on RARRES1

1. RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY-bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-RARRES1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>17 publications with RARRES1 and Neoplasms
Head and Neck Neoplasms Antibodies	>6 publications with RARRES1 and Head and Neck Neoplasms
Prostatic Neoplasms Antibodies	>5 publications with RARRES1 and Prostatic Neoplasms
Prostatic Hyperplasia Antibodies	>4 publications with RARRES1 and Prostatic Hyperplasia
Intestinal Diseases Antibodies	>3 publications with RARRES1 and Intestinal Diseases
Melanoma Antibodies	>3 publications with RARRES1 and Melanoma
Colorectal Neoplasms Antibodies	>2 publications with RARRES1 and Colorectal Neoplasms
Skin Diseases Antibodies	>2 publications with RARRES1 and Skin Diseases
Adenocarcinoma Antibodies	>2 publications with RARRES1 and Adenocarcinoma
Esophageal Neoplasms Antibodies	>2 publications with RARRES1 and Esophageal Neoplasms

Organs/Tissues associated with anti-RARRES1 antibody

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>6 publications with RARRES1 and Prostate
Skin Antibodies	>5 publications with RARRES1 and Skin
Brain Antibodies	>3 publications with RARRES1 and Brain
Stomach Antibodies	>2 publications with RARRES1 and Stomach
Lung Antibodies	>2 publications with RARRES1 and Lung
Bone Antibodies	>2 publications with RARRES1 and Bone
Esophagus Antibodies	>1 publications with RARRES1 and Esophagus
Connective Tissue Antibodies	>1 publications with RARRES1 and Connective Tissue
Adipose Tissue Antibodies	>1 publications with RARRES1 and Adipose Tissue
Kidney Antibodies	>1 publications with RARRES1 and Kidney