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ATOX1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6184504

This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ATOX1, Monoclonal Antibody
Full Product Name
ATOX1 (ATX1 Antioxidant Protein 1 Homolog (yeast), ATX1, HAH1, MGC138453, MGC138455) (PE)
Product Gene Name
Product Synonym Names
ATX1 Antioxidant Protein 1 Homolog (yeast); ATX1; HAH1; MGC138453; MGC138455
Clonality
Monoclonal
Isotype
IgG
Clone Number
3G11
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified
Specificity
Recognizes ATOX1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
9.5 kDa (88aa), confirmed by MALDI-TOF.
OMIM
602270
3D Structure
ModBase 3D Structure for O00244
Immunogen
ATOX1 (NP_004036, 1aa-68aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MPKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDTLLATLKKTGKTVSYLGLE
Conjugate
PE

Product Categories/Family for anti-ATOX1 antibody

Applications Tested/Suitable for anti-ATOX1 antibody
Western Blot (WB)
Application Notes for anti-ATOX1 antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ATOX1 antibody

ATOX1 monoclonal antibody (M04), clone 3G11. Western Blot analysis of ATOX1 expression in HepG2 (Cat # L019V1).
Mouse Anti-ATOX1 Monoclonal Antibody – Cat# MBS6184504

Western Blot (WB) of anti-ATOX1 antibody

ATOX1 monoclonal antibody (M04), clone 3G11. Western Blot analysis of ATOX1 expression in COLO 320 HSR (Cat # L020V1).
Mouse Anti-ATOX1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6184504

Western Blot (WB) of anti-ATOX1 antibody

ATOX1 monoclonal antibody (M04), clone 3G11. Western Blot analysis of ATOX1 expression in human kidney.
Mouse Anti-ATOX1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6184504

Testing Data of anti-ATOX1 antibody

Detection limit for recombinant GST tagged ATOX1 is approximately 0.1ng/ml as a capture antibody.
Mouse Anti-ATOX1 Monoclonal Antibody, Testing Data – Cat# MBS6184504

Other Notes

Small volumes of anti-ATOX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATOX1 purchase

MBS6184504 is an antibody targeting ATOX1. Also known as ATOX1 (ATX1 Antioxidant Protein 1 Homolog (yeast), ATX1, HAH1, MGC138453, MGC138455) (PE). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ATOX1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
copper transport protein ATOX1
NCBI Official Synonym Full Names
antioxidant 1 copper chaperone
NCBI Official Symbol
ATOX1
NCBI Official Synonym Symbols
ATX1; HAH1
UniProt Protein Name
Copper transport protein ATOX1
UniProt Synonym Protein Names
Metal transport protein ATX1
UniProt Gene Name
ATOX1
UniProt Synonym Gene Names
HAH1
UniProt Entry Name
ATOX1_HUMAN
NCBI Protein Information
copper transport protein ATOX1

UniProt Comments for ATOX1

ATOX1: Could bind and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense. Belongs to the ATX1 family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: cytosol

Molecular Function: metallochaperone activity; copper ion transmembrane transporter activity; copper ion binding; copper chaperone activity; copper-dependent protein binding

Biological Process: response to reactive oxygen species; cellular copper ion homeostasis; response to oxidative stress; copper ion transport; intracellular copper ion transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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