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Monocarboxylate Transporter 5 (SLC16A4) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS618530

Lactic acid transport is mediated by a group of proton-linked membrane transporters called monocarboxylic acid transporters (MCTs). At least 9 MCT-related proteins (MCT1-9) have been identified in mammals that are expressed in a tissue specific… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Monocarboxylate Transporter 5 (SLC16A4), Polyclonal Antibody
Full Product Name
Monocarboxylate Transporter 5 (MCT5, MOT5)
Product Gene Name
Product Synonym Names
Anti -Monocarboxylate Transporter 5 (MCT5, MOT5)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human Monocarboxylate Transporter 5 (MCT5/MOT5). Reactivity with other members of the MCT family is unlikely because the immunogen shows no significant sequence homology with other MCTs.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
54,022 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (110905505..110933636, complement). Location: 1p13.3
OMIM
603878
3D Structure
ModBase 3D Structure for O15374
Immunogen
Synthetic peptide corresponding to a 19aa sequence within the cytoplasmic domain #4, near the C-terminus of human MCT5 conjugated to KLH. Species Sequence Homology: mouse MCT5, 65%.
Applications Tested/Suitable for anti-SLC16A4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SLC16A4 antibody
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide per well.
Western Blot: 1-5ug/ml using ECL.

Other Notes

Small volumes of anti-SLC16A4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLC16A4 purchase

MBS618530 is an antibody targeting SLC16A4. Also known as Monocarboxylate Transporter 5 (MCT5, MOT5). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC16A4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
monocarboxylate transporter 5 isoform 1
NCBI Official Synonym Full Names
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
NCBI Official Symbol
SLC16A4
NCBI Official Synonym Symbols
MCT4; MCT5
UniProt Protein Name
Monocarboxylate transporter 5
UniProt Synonym Protein Names
Monocarboxylate transporter 4; MCT 4; Solute carrier family 16 member 4
UniProt Gene Name
SLC16A4
UniProt Synonym Gene Names
MCT4; MCT5
UniProt Entry Name
MOT5_HUMAN
NCBI Protein Information
monocarboxylate transporter 5; MCT 4; MCT 5; OTTHUMP00000013008; OTTHUMP00000013284; OTTHUMP00000229648; monocarboxylate transporter 4; solute carrier family 16 member 4; solute carrier family 16 (monocarboxylic acid transporters), member 4

UniProt Comments for SLC16A4

SLC16A4: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: membrane; integral to plasma membrane; integral to membrane

Molecular Function: monocarboxylic acid transmembrane transporter activity; symporter activity

Biological Process: monocarboxylic acid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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