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P53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS618698

Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identi ed recently and designated PUMA (for p53… More details

$850 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3, Polyclonal Antibody
Full Product Name
p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3, CT (PUMA/bbc3)
Product Synonym Names
Anti -p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3, CT (PUMA/bbc3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide before the addition of glycerol to 40%.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes PUMA-a. Detects a band at ~23kD. A lower band at ~16kD was detected in MOLT4 and U937 cells, which may represent the PUMA-b. Species Crossreactivity: Mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Synthetic peptide corresponding to aa180 to 193 (PLPRGHRAPEMEPN) of human PUMA-a. This sequence is identical between the alpha and beta forms of the PUMA proteins.
Positive Control
K562 or 3T3 cell lysate

Product Categories/Family for anti-p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 antibody

Antibodies; Abs to Apoptosis
Applications Tested/Suitable for anti-p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 antibody
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1-2ug/ml

Immunohistochemistry (IHC) of anti-p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 antibody

Immunohistochemical analysis of MBS618698.
Rabbit Anti-P53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 Polyclonal Antibody – Cat# MBS618698

Western Blot (WB) of anti-p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 antibody

Western Blot analysis of MBS618698.
Rabbit Anti-P53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS618698

Other Notes

Small volumes of anti-p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3 purchase

MBS618698 is an antibody targeting p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3. Also known as p53 Upregulated Modulator of Apoptosis/Bcl 2 Binding Component 3, CT (PUMA/bbc3). Reactive in Human, Mouse. Host: Rabbit.
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