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COPS6 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6189570

MBS6189570 is an antibody targeting COPS6. Also known as COPS6 (COP9 Signalosome Complex Subunit 6, Signalosome Subunit 6, SGN6, JAB1-Containing Signalosome Subunit 6, hVIP, Vpr-interacting Protein, MOV34 Homolog, CSN6, HVIP) (MaxLight 405). Reactive in… More details

$960 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
COPS6, Monoclonal Antibody
Full Product Name
COPS6 (COP9 Signalosome Complex Subunit 6, Signalosome Subunit 6, SGN6, JAB1-Containing Signalosome Subunit 6, hVIP, Vpr-interacting Protein, MOV34 Homolog, CSN6, HVIP) (MaxLight 405)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2H5
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human COPS6.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
36,163 Da
Immunogen
Partial recombinant corresponding to aa30-327 from human COPS6 (AAH02520) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
VMACGVTGSVSVALHPLVILNISDHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKIIIDKEYYYTKEEQFKQVFKELEFLGWYTTGGPPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTDLPVSVFESVIDIINGEATMLFAELTYTLATEEAERIGVDHVARMTATGSGENSTVAEHLIAQHSAIKMLHSRVKLILEYVKASEAGEVPFNHEILREAYALCHCLPVLSTDKFKTDFYDQCN
Conjugate
MaxLight405

Product Categories/Family for anti-COPS6 antibody

Applications Tested/Suitable for anti-COPS6 antibody
FLISA, Immunohistochemistry (IHC) Paraffin
Application Notes for anti-COPS6 antibody
IHC-P: 1.5ug/ml
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-COPS6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for COPS6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis), mRNA
NCBI Official Synonym Full Names
COP9 signalosome subunit 6
NCBI Official Symbol
COPS6
NCBI Official Synonym Symbols
CSN6; MOV34-34KD
NCBI Protein Information
COP9 signalosome complex subunit 6

NCBI Summary for COPS6

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-COPS6 antibody

 Products by Pathway  Pathway Diagram
 NOD Pathway antibodies  NOD Pathway Diagram

Organs/Tissues associated with anti-COPS6 antibody

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