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CRYGC Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6189629

MBS6189629 is an antibody targeting CRYGC. Also known as CRYGC (Gamma-crystallin C, Gamma-C-crystallin, Gamma-crystallin 2-1, Gamma-crystallin 3, CRYG3) (MaxLight 405). Reactive in Human. Host: Mouse. Crystallins are the dominant structural components of the… More details

$960 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CRYGC, Monoclonal Antibody
Full Product Name
CRYGC (Gamma-crystallin C, Gamma-C-crystallin, Gamma-crystallin 2-1, Gamma-crystallin 3, CRYG3) (MaxLight 405)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
7C4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human CRYGC.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
23.5kDa (198aa), confirmed by MALDI-TOF
OMIM
123680
3D Structure
ModBase 3D Structure for P07315
Immunogen
Partial recombinant corresponding to aa75-174 from human CRYGC (NP_066269) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
SIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
Conjugate
MaxLight405

Product Categories/Family for anti-CRYGC antibody

Applications Tested/Suitable for anti-CRYGC antibody
FLISA, Western Blot (WB)
Application Notes for anti-CRYGC antibody
Applications are based on unconjugated antibody.

Other Notes

Small volumes of anti-CRYGC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CRYGC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
gamma-crystallin C
NCBI Official Synonym Full Names
crystallin gamma C
NCBI Official Symbol
CRYGC
NCBI Official Synonym Symbols
CCL; CRYG3; CTRCT2
UniProt Protein Name
Gamma-crystallin C
UniProt Synonym Protein Names
Gamma-C-crystallin; Gamma-crystallin 2-1; Gamma-crystallin 3
Protein Family
UniProt Gene Name
CRYGC
UniProt Synonym Gene Names
CRYG3
UniProt Entry Name
CRGC_HUMAN
NCBI Protein Information
gamma-crystallin C

NCBI Summary for CRYGC

This gene encodes a member of the beta/gamma-crystallin family of proteins. Crystallins constitute the major proteins of vertebrate eye lens and maintain the transparency and refractive index of the lens. This gene and several family members are present in a gene cluster on chromosome 2. Mutations in this gene have been shown to cause multiple types of cataract, including Coppock-like cataract and zonular pulverulent cataract, among others. [provided by RefSeq, Jan 2015]
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UniProt Comments for CRYGC

CRYGC: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. Gamma-crystallins are involved in cataract formation.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 2q33.3

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; structural constituent of eye lens

Biological Process: camera-type eye development; visual perception

Disease: Cataract 2, Multiple Types
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-CRYGC antibody

Organs/Tissues associated with anti-CRYGC antibody

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >29 publications with CRYGC and Eye
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