Rabbit Anti-Nna1 Polyclonal Antibody – Cat# MBS619079

Western blot analysis of extracts from fetal and adult rat brain using MBS619079.

Nna1 Antibody – Rabbit Polyclonal

Name: Nna1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS619079
Price: 760 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619079

Nervous system nuclear protein induced by axotomy 1 (Nna1, AGTPBP1 or cytosolic carboxypeptidase-1) is related to zinc carboxypeptidases and contains an ATP/GTP binding motif, a basic and a bipartite nuclear localization signal. Nna1 expression is rapidly… More details

$760 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Nna1, Polyclonal Antibody

Full Product Name

Nna1 (Nervous system nuclear protein induced by axotomy 1, AGTPBP1, Cytosolic carboxypeptidase-1)

Product Synonym Names

Anti -Nna1 (Nervous system nuclear protein induced by axotomy 1, AGTPBP1, Cytosolic carboxypeptidase-1)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

Supplied as a liquid in 10mM sodium HEPES pH 7.5, 0.1%, 150mM NaCl, 100ug/ml BSA and 50% glycerol.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recongnizes endog-enous levels of human total Nna1 protein. Species crossreactivity: mouse, rat.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Immunogen

Synthetic peptide corresponding to residues surrounding Asp1175 of human Nna1 protein (KLH-coupled).

Product Categories/Family for anti-Nna1 antibody

Antibodies; Abs to Enzymes; Carboxypeptidase

Applications Tested/Suitable for anti-Nna1 antibody

Western Blot (WB), Immunoprecipitation (IP)

Application Notes for anti-Nna1 antibody

Suitable for use in Western Blot and Immunoprecipitation.
Dilution: Western Blot: 1:1000 Incubate membrane with diluted antibody in 5% w/v BSA, 1X TBS,
0.1% Tween-20 at 4 degree C with gentle shaking, overnight.
Immunoprecipitation: 1:50

Other Notes

Small volumes of anti-Nna1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nna1 purchase

MBS619079 is an antibody targeting Nna1. Also known as Nna1 (Nervous system nuclear protein induced by axotomy 1, AGTPBP1, Cytosolic carboxypeptidase-1). Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Nna1. It may not necessarily be applicable to this product.

NCBI GI #

11528062

NCBI Accession #

AAG37102.1

NCBI Official Full Name

nuclear ATP/GTP-binding protein

UniProt Comments for Nna1

Nna1: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Interacts with MYLK. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; EC 3.4.17.-

Cellular Component: mitochondrion; cytoplasm; nucleus; cytosol

Molecular Function: peptidase activity; tubulin binding; protein binding; zinc ion binding; metallopeptidase activity; hydrolase activity; carboxypeptidase activity; metal ion binding; metallocarboxypeptidase activity

Biological Process: mitochondrion organization and biogenesis; neurotransmitter metabolic process; retina development in camera-type eye; olfactory bulb development; neuromuscular process; cerebellar Purkinje cell differentiation; cerebellar Purkinje cell layer development; cerebellum development; eye photoreceptor cell differentiation; proteolysis; adult walking behavior

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.