Rabbit Anti-TRIM30A Polyclonal Antibody – Cat# MBS619312

Western blot analysis of TRIM30 in human ovary tissue lysate with TRIM30 antibody at (A) 1 and (B) 2 ug/ml.

TRIM30A Antibody – Rabbit Polyclonal

Name: TRIM30A Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS619312
Price: 850 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS619312

TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses. The TRIM protein family is an expanding family of RING ('really… More details

$850 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TRIM30 (Trim30a), Polyclonal Antibody

Full Product Name

TRIM30, CT (Tripartite motif-containing 30, Rpt-1, Rpt1, down regulatory protein of interleukin 2 receptor)

Product Gene Name

anti-Trim30a antibody

Product Synonym Names

Anti -TRIM30, CT (Tripartite motif-containing 30, Rpt-1, Rpt1, down regulatory protein of interleukin 2 receptor)

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, 0.02% sodium azide.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes human TRIM30.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

57,330 Da

Chromosome Location

Chromosome: 7; NC_000073.5 (111557539..111613707, complement). Location: 7 E3; 7 50.4 cM

3D Structure

ModBase 3D Structure for P15533

Immunogen

Synthetic peptide corresponding to 16aa from near the carboxy terminus of the human TRIM30.

Positive Control

Human Ovary Tissue Lysate

Product Categories/Family for anti-Trim30a antibody

Antibodies; Abs to Transcription Factors; TRIM (Tripartite Motif)

Applications Tested/Suitable for anti-Trim30a antibody

Western Blot (WB)

Application Notes for anti-Trim30a antibody

Suitable for use in Western Blot.
Dilution: Western Blot: 1-2ug/ml

Other Notes

Small volumes of anti-Trim30a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Trim30a purchase

MBS619312 is an antibody targeting Trim30a. Also known as TRIM30, CT (Tripartite motif-containing 30, Rpt-1, Rpt1, down regulatory protein of interleukin 2 receptor). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Trim30a. It may not necessarily be applicable to this product.

NCBI GI #

125347379

NCBI GeneID

20128

NCBI Accession #

NP_033125.2

UniProt Primary Accession #

P15533

UniProt Secondary Accession #

Q99K55; Q99PQ7; Q99PQ8; Q99PQ9

UniProt Related Accession #

P15533; Q3UUN0; Q3UV85; Q3UZ29

GenBank Nucleotide #

NM_009099.2

NCBI Official Full Name

tripartite motif-containing protein 30

NCBI Official Synonym Full Names

tripartite motif-containing 30A

NCBI Official Symbol

Trim30a

NCBI Official Synonym Symbols

Rpt1; Rpt-1; Trim30

UniProt Protein Name

Tripartite motif-containing protein 30

UniProt Synonym Protein Names

Down regulatory protein of interleukin-2 receptor

Protein Family

Tripartite motif-containing protein

UniProt Gene Name

Trim30

UniProt Synonym Gene Names

Rpt-1; Rpt1

UniProt Entry Name

TRI30_MOUSE

NCBI Protein Information

tripartite motif-containing protein 30; OTTMUSP00000020742; tripartite motif protein 30; tripartite motif-containing 30; regulatory protein, T lymphocyte 1; down regulatory protein of interleukin-2 receptor

UniProt Comments for Trim30a

TRIM30A: Trans-acting factor that regulates gene expression of interleukin 2 receptor alpha chain. May affect IL2R-alpha expression through cis-acting negative regulatory elements or through competition with proteins that bind to enhancer or activator sequences. Negatively regulates Toll-like receptor (TLR)-mediated activation of NFKB by promoting degradation of TAB2 and TAB3 and preventing TRAF6 autoubiquitination. Negatively regulates production of reactive oxygen species (ROS) which inhibits activation of the NLRP3 inflammasome complex. This, in turn, regulates activation of CASP1 and subsequent cleavage of IL1B and IL18. No activity detected against a range of retroviruses including a number of lentiviruses, gammaretroviruses and betaretroviruses

Cellular Component: cytoplasm; intracellular; nucleus

Molecular Function: DNA binding; zinc ion binding; metal ion binding

Biological Process: protein autoubiquitination; regulation of transcription, DNA-dependent; positive regulation of virion penetration into host cell; transcription, DNA-dependent; positive regulation of protein catabolic process; negative regulation of interleukin-6 production; negative regulation of toll-like receptor signaling pathway; negative regulation of tumor necrosis factor production

Research Articles on Trim30a

1. TRIM30 is a negative regulator of NLRP3 inflammasome activation and provide insights into the role of TRIM30 in maintaining inflammatory responses.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-Trim30a antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with Trim30a and Blood